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Tusc1 Gene Detail
Summary
  • Symbol
    Tusc1
  • Name
    tumor suppressor candidate 1
  • Synonyms
    2200001D17Rik, TSG-9
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684283
    NCBI Gene: 69136
Location & Maps
more
  • Sequence Map
    Chr4:93334138-93335511 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1374 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 43.25 cM, cytoband C5
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TUSC1, tumor suppressor candidate 1
  • Vertebrate Orthologs
    5
  • Human Ortholog
    TUSC1, tumor suppressor candidate 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CCDC89B, TSG9, TSG-9
  • Links
    NCBI Gene ID: 286319
    neXtProt AC: NX_Q2TAM9
    UniProt: Q2TAM9

  • Chr Location
    9p21.2; chr9:25676389-25678858 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Tusc1
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007809 VEGA Gene Model | MGI Sequence Detail 1374 C57BL/6J ±  kb
transcript OTTMUST00000017798 VEGA | MGI Sequence Detail 1374 Not Applicable  
polypeptide OTTMUSP00000008187 VEGA | MGI Sequence Detail 205 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    63 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 1
    cDNA 5

    Microarray probesets 3
Other
Accession IDs
less
MGI:1916386
References
more
  • Summaries
    All 26
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:23094 Davisson MT, New chromosome aberrations. Mouse News Lett. 1988;80:166
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
05/16/2017
MGI 6.09
The Jackson Laboratory