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Akap11
Gene Detail
Symbol

Name
ID
Akap11
A kinase (PRKA) anchor protein 11
MGI:2684060
Synonyms
6330501D17Rik, mKIAA0629
Feature Type
protein coding gene
Genetic Map
Chromosome 14
41.46 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr14:78492246-78536808 bp, - strand
From VEGA annotation of GRCm38

  44563 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8279  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: AKAP11
Gene Tree: Akap11

Human
homologs
AKAP11, A kinase (PRKA) anchor protein 11
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 11215
neXtProt AC: NX_Q9UKA4

Human Synonyms: AKAP-11, AKAP220, PPP1R44, PRKA11

Human Chr (Location): 13q14.11; chr13:42271481-42323267 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(4) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Akap11 interacts with 432 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process regulation of catalytic activity, regulation of phosphorylation, ...
Component cytoplasm, peroxisome, ...
Function kinase regulator activity, protein complex scaffold, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (120)    Tissues (13)    Images (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 120
cDNA source data(113)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase akap11    NEW 
Molecular
reagents
All nucleic(113) cDNA(113)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000032614 (Evidence)
Ensembl Gene Model ENSMUSG00000022016 (Evidence)
Entrez Gene 219181 (Evidence)
UniGene 89413
DFCI TC1629260, TC1625081, TC1600994
DoTS DT.489893, DT.91338213, DT.99854926
NIA Mouse Gene Index U035800
Consensus CDS Project CCDS49549.1
International Mouse Phenotyping Consortium Status Akap11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032614 VEGA Gene Model | MGI Sequence Detail 44563 C57BL/6J ±  kb
transcript OTTMUST00000081112 VEGA | MGI Sequence Detail 9367 Not Applicable 
polypeptide OTTMUSP00000043333 VEGA | MGI Sequence Detail 1895 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(11) UniProt(4)
Polymorphisms
SNPs within 2kb(310 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018292 A-kinase anchor 110kDa, C-terminal
InterPro IPR008382 SPHK1-interactor/A-kinase anchor 110kDa
Protein Ontology PR:000003885 A-kinase anchor protein 11
References
(Earliest) J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
(Latest) J:177007 Day ME, et al., Isoform-specific targeting of PKA to multivesicular bodies. J Cell Biol. 2011 Apr 18;193(2):347-63
All references(38)
Other
accession IDs
MGI:2684926

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory