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Vmn2r81 Gene Detail
Summary
  • Symbol
    Vmn2r81
  • Name
    vomeronasal 2, receptor 81
  • Synonyms
    EC1-VR2, pheromone recepter, V2rf2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684056
    NCBI Gene: 216144
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr10:79083611-79130369 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    120 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684056
 protein coding gene Chr10:79083526-79130369 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017441
 protein coding gene Chr10:79612410-79764366 (+)
A/J MGP_AJ_G0017420
 protein coding gene Chr10:77031740-77074562 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0017381
 protein coding gene Chr10:77020612-77369002 (+)
C3H/HeJ MGP_C3HHeJ_G0017205
 protein coding gene Chr10:79291686-79340083 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017836
 protein coding gene Chr10:82544984-82595291 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0017176
 protein coding gene Chr10:85583566-85604669 (+)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0017276
 protein coding gene Chr10:75382756-75446696 (+)
LP/J MGP_LPJ_G0017352
 protein coding gene Chr10:80289459-80324108 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0017875
 protein coding gene Chr10:79075584-79150418 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0016341
 protein coding gene Chr10:78182056-78217528 (+)
WSB/EiJ MGP_WSBEiJ_G0016832
 protein coding gene Chr10:78982112-79025845 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotypes from multigenic genotypes
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit vomeronasal sensory neuron axons that spread out diffusely over the posterior accessory olfactory bulb and extend abnormally into the anterior olfactory bulb.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 216144 NCBI Gene Model | MGI Sequence Detail 46759 C57BL/6J ±  kb
    transcript NM_175936 RefSeq | MGI Sequence Detail 3276 C57BL/6  
    polypeptide NP_787950 RefSeq | MGI Sequence Detail 865 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR000337 GPCR, family 3
      IPR017978 GPCR family 3, C-terminal
      IPR000068 GPCR, family 3, extracellular calcium-sensing receptor-related
      IPR011500 GPCR, family 3, nine cysteines domain
      IPR038550 GPCR, family 3, nine cysteines domain superfamily
      IPR004073 GPCR, family 3, vomeronasal receptor, type 2
      IPR028082 Periplasmic binding protein-like I
      IPR001828 Receptor, ligand binding region
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 2

      Microarray probesets 2
    References
    more
    • Summaries
      All 27
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:262032 Akiyoshi S, et al., Subpopulations of vomeronasal sensory neurons with coordinated coexpression of type 2 vomeronasal receptor genes are differentially dependent on Vmn2r1. Eur J Neurosci. 2018 Apr;47(7):887-900
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    04/16/2024
    MGI 6.23     		The Jackson Laboratory