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Vmn2r81
Gene Detail
 Symbol
Name
ID
Vmn2r81
vomeronasal 2, receptor 81
MGI:2684056
Synonyms EC1-VR2, pheromone recepter, V2rf2
Feature Type protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:79247777-79294535 bp, + strand
From VEGA annotation of GRCm38

  46759 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:83483  Vertebrate Homology Class
3 mouse

Protein SuperFamily: metabotropic glutamate receptor-like protein
Gene Tree: Vmn2r81

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit vomeronasal sensory neuron axons that spread out diffusely over the posterior accessory olfactory bulb and extend abnormally into the anterior olfactory bulb.
 
Interactions
Vmn2r81 interacts with 148 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process G-protein coupled receptor signaling pathway, positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway, ...
Component cell, cytosol, ...
Function G-protein coupled receptor activity, signal transducer activity
External Resources: FuncBase
Expression
cDNA source data(1)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(2) cDNA(1) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000032820 (Evidence)
Ensembl Gene ModelENSMUSG00000055515 (Evidence)
Entrez Gene216144 (Evidence)
UniGene246574
DoTSDT.101282144
NIA Mouse Gene IndexU126583
Consensus CDS ProjectCCDS23976.1
International Mouse Knockout Project StatusVmn2r81
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032820 VEGA Gene Model | MGI Sequence Detail 46759 C57BL/6J ±  kb
transcript OTTMUST00000081748 VEGA | MGI Sequence Detail 3276 Not Applicable 
polypeptide OTTMUSP00000043773 VEGA | MGI Sequence Detail 865 Not Applicable 

For the selected sequences
All sequences(14) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(131 from dbSNP Build 137)    SNPs within 2kb including multiple locations(149)
Protein-related
information
ResourceIDDescription
InterPro IPR001828 Extracellular ligand-binding receptor
InterPro IPR000337 GPCR, family 3
InterPro IPR017978 GPCR, family 3, C-terminal
InterPro IPR011500 GPCR, family 3, nine cysteines domain
InterPro IPR004073 GPCR, family 3, vomeronasal receptor, type 2
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:207447 Leinders-Zufall T, et al., A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J Neurosci. 2014 Apr 9;34(15):5121-33
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory