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Kcnk12 Gene Detail
Summary
  • Symbol
    Kcnk12
  • Name
    potassium channel, subfamily K, member 12
  • Synonyms
    mntk1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684043
    NCBI Gene: 210741
  • Gene Overview
    MyGene.info: KCNK12
Location & Maps
more
  • Sequence Map
    Chr17:87745837-87797994 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      52158 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 57.87 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    KCNK12, potassium two pore domain channel subfamily K member 12
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KCNK12, potassium two pore domain channel subfamily K member 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    K2p12.1, THIK2, THIK-2
  • Links
    NCBI Gene ID: 56660
    neXtProt AC: NX_Q9HB15
    UniProt: Q9HB15

  • Chr Location
    2p16.3; chr2:47520775-47570331 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11107
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KCNK12
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050138 Ensembl Gene Model | MGI Sequence Detail 52158 C57BL/6J ±  kb
transcript ENSMUST00000055221 Ensembl | MGI Sequence Detail 1936 Not Applicable  
polypeptide ENSMUSP00000053595 Ensembl | MGI Sequence Detail 430 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    536 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR013099 Potassium channel domain
    IPR003280 Two pore domain potassium channel
    IPR005410 Two pore domain potassium channel, THIK
Molecular
Reagents
less
  • All nucleic 3
    cDNA 2
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 17
    Developmental Gene Expression 1
    Phenotypes 2
  • Earliest
    J:119550 Harrell MD, et al., Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol Genomics. 2007 Feb 12;28(3):273-83
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory