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Ttc5 Gene Detail
Summary
  • Symbol
    Ttc5
  • Name
    tetratricopeptide repeat domain 5
  • Synonyms
    MGC:38092
  • Feature Type
    protein coding gene
  • IDs
    MGI:2683584
    NCBI Gene: 219022
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr14:50765415-50785519 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 26.24 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    251 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2683584
protein coding gene Chr14:50765409-50785520 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021256
protein coding gene Chr14:44709398-44730821 (-)
A/J MGP_AJ_G0021210
protein coding gene Chr14:43376684-43397347 (-)
AKR/J MGP_AKRJ_G0021186
protein coding gene Chr14:45006495-45026589 (-)
BALB/cJ MGP_BALBcJ_G0021213
protein coding gene Chr14:43490713-43511115 (-)
C3H/HeJ MGP_C3HHeJ_G0020995
protein coding gene Chr14:44826878-44851478 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021649
protein coding gene Chr14:46525756-46545877 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019202
protein coding gene Chr14:42716943-42737749 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0020962
protein coding gene Chr14:48009090-48034290 (-)
DBA/2J MGP_DBA2J_G0021086
protein coding gene Chr14:43272410-43293584 (-)
FVB/NJ MGP_FVBNJ_G0021067
protein coding gene Chr14:42900007-42920284 (-)
LP/J MGP_LPJ_G0021154
protein coding gene Chr14:44989486-45012475 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021095
protein coding gene Chr14:47490897-47517641 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021679
protein coding gene Chr14:44499232-44519807 (-)
PWK/PhJ MGP_PWKPhJ_G0020269
protein coding gene Chr14:40171083-40191888 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020094
protein coding gene Chr14:40659015-40680381 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    TTC5, tetratricopeptide repeat domain 5
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TTC5, tetratricopeptide repeat domain 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Strap
  • Links
    NCBI Gene ID: 91875
    neXtProt AC: NX_Q8N0Z6
    UniProt: Q8N0Z6

  • Chr Location
    14q11.2; chr14:20289131-20305994 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006288 Ensembl Gene Model | MGI Sequence Detail 20105 C57BL/6J ±  kb
transcript ENSMUST00000006451 Ensembl | MGI Sequence Detail 1842 Not Applicable  
polypeptide ENSMUSP00000006451 Ensembl | MGI Sequence Detail 440 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 53
    cDNA 53

    Microarray probesets 2
Other
Accession IDs
less
MGI:2145844
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:273555 Pressly JD, et al., TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury. Sci Rep. 2017 Mar 3;7:43196

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory