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Ssh3 Gene Detail
Summary
  • Symbol
    Ssh3
  • Name
    slingshot protein phosphatase 3
  • Synonyms
    SSH-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2683546
    NCBI Gene: 245857
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:4311696-4319208 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 3.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    34 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2683546
 protein coding gene Chr19:4311696-4319261 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024659
 protein coding gene Chr19:1110534-1118038 (-)
A/J MGP_AJ_G0024625
 protein coding gene Chr19:1064621-1072125 (-)
AKR/J MGP_AKRJ_G0024598
 protein coding gene Chr19:1094386-1101890 (-)
BALB/cJ MGP_BALBcJ_G0024625
 protein coding gene Chr19:1054898-1062352 (-)
C3H/HeJ MGP_C3HHeJ_G0024393
 protein coding gene Chr19:1090894-1098398 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025073
 protein coding gene Chr19:1156678-1164182 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022502
 protein coding gene Chr19:1004601-1012297 (-)
CAST/EiJ MGP_CASTEiJ_G0023865
 protein coding gene Chr19:1103092-1110581 (-)
CBA/J MGP_CBAJ_G0024364
 protein coding gene Chr19:1212479-1219983 (-)
DBA/2J MGP_DBA2J_G0024492
 protein coding gene Chr19:1026229-1033733 (-)
FVB/NJ MGP_FVBNJ_G0024459
 protein coding gene Chr19:1036221-1043725 (-)
LP/J MGP_LPJ_G0024578
 protein coding gene Chr19:1117119-1124573 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024489
 protein coding gene Chr19:1150699-1158203 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025120
 protein coding gene Chr19:1090453-1097990 (-)
PWK/PhJ MGP_PWKPhJ_G0023611
 protein coding gene Chr19:1078985-1086499 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023416
 protein coding gene Chr19:1076041-1083692 (-)
WSB/EiJ MGP_WSBEiJ_G0023927
 protein coding gene Chr19:1087477-1094981 (-)



Homology
more
  • Human Ortholog
    SSH3, slingshot protein phosphatase 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SSH3, slingshot protein phosphatase 3
  • Synonyms
    SSH3L
  • Links
    NCBI Gene ID: 54961
    neXtProt AC: NX_Q8TE77
    UniProt: Q8TE77

  • Chr Location
    11q13.2; chr11:67303478-67312607 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Mice homozygous for a null allele exhibit no abnormal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    747
  • Tissues
    31
  • cDNA Data
    43
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034616 Ensembl Gene Model | MGI Sequence Detail 7513 C57BL/6J ±  kb
transcript ENSMUST00000236794 Ensembl | MGI Sequence Detail 2062 Not Applicable  
polypeptide ENSMUSP00000158486 Ensembl | MGI Sequence Detail 653 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 43
    cDNA 43

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:89966 Ohta Y, et al., Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin. Genes Cells. 2003 Oct;8(10):811-24
  • Latest
    J:233532 Scekic-Zahirovic J, et al., Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. EMBO J. 2016 May 17;35(10):1077-97
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory