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Mast3 Gene Detail
Summary
  • Symbol
    Mast3
  • Name
    microtubule associated serine/threonine kinase 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2683541
    NCBI Gene: 546071
Location & Maps
more
  • Sequence Map
    Chr8:70778117-70792433 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14317 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    MAST3, microtubule associated serine/threonine kinase 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MAST3, microtubule associated serine/threonine kinase 3
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 23031
    neXtProt AC: NX_O60307

  • Chr Location
    19p13.11; chr19:18097764-18151692 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 66191
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: MAST3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Mast3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031833 Ensembl Gene Model | MGI Sequence Detail 14317 C57BL/6J ±  kb
transcript ENSMUST00000166004 Ensembl | MGI Sequence Detail 5334 Not Applicable  
polypeptide ENSMUSP00000128703 Ensembl | MGI Sequence Detail 1305 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    168 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010197 microtubule-associated serine/threonine-protein kinase 3
  • EC
  • InterPro Domains
    IPR000961 AGC-kinase, C-terminal
    IPR015022 Microtubule-associated serine/threonine-protein kinase, domain
    IPR023142 Microtubule-associated serine/threonine-protein kinase, pre-PK domain
    IPR001478 PDZ domain
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain
    IPR008271 Serine/threonine-protein kinase, active site
Molecular
Reagents
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  • All nucleic 55
    cDNA 55

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory