About   Help   FAQ
Tapt1
Gene Detail
Symbol

Name
ID
Tapt1
transmembrane anterior posterior transformation 1
MGI:2683537
Synonyms
4932414K18Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
24.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:44175164-44226606 bp, - strand
From Ensembl annotation of GRCm38

  51443 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:80206  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: TAPT1
Gene Tree: Tapt1

Human
homologs
TAPT1, transmembrane anterior posterior transformation 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 202018
neXtProt AC: NX_Q6NXT6

Human Synonyms: CMVFR

Human Chr (Location): 4p15.32; chr4:16160505-16227158 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Chemically induced (ENU)(2) Gene trapped(4) Radiation induced(2) Targeted(3) Transgenic(1)
Genomic Mutations involving Tapt1 (3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for an ENU mutation causing a truncation exhibit vertebral trasnformations and defects in rib attachment and the xiphoid process. Mice homozygous for a transgenic gene disruption exhibit cleft palate and possible anemia.
 
Mutations Annotated to Human Diseases (2)    Phenotype Images(4)
Interactions
Tapt1 interacts with 226 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process embryonic skeletal system development, in utero embryonic development, ...
Component integral component of membrane, membrane
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (10)    Tissues (5)    Images (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 10
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tapt1    NEW 
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000046985 (Evidence)
Entrez Gene 231225 (Evidence)
DFCI TC1636491, TC1615744, TC1577576
DoTS DT.534115, DT.60100501
NIA Mouse Gene Index U026160, U205892
Consensus CDS Project CCDS19270.1
International Mouse Phenotyping Consortium Status Tapt1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046985 Ensembl Gene Model | MGI Sequence Detail 51443 C57BL/6J ±  kb
transcript ENSMUST00000055128 Ensembl | MGI Sequence Detail 3487 Not Applicable 
polypeptide ENSMUSP00000062110 Ensembl | MGI Sequence Detail 564 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(8) UniProt(1)
Polymorphisms
SNPs within 2kb(277 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008010 Membrane protein,Tapt1/CMV receptor
Protein Ontology PR:000016055 transmembrane anterior posterior transformation protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory