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Rere Gene Detail
Summary
  • Symbol
    Rere
  • Name
    arginine glutamic acid dipeptide (RE) repeats
  • Synonyms
    1110033A15Rik, Atr2, atrophin-2, eye03, eyem03Jus, eyes3, mKIAA0458
  • Feature Type
    protein coding gene
  • IDs
    MGI:2683486
    NCBI Gene: 68703
  • Gene Overview
    MyGene.info: RERE
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr4:150281646-150621966 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      340321 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 81.34 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    RERE, arginine-glutamic acid dipeptide repeats
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RERE, arginine-glutamic acid dipeptide repeats
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARG, ARP, ATN1L, DNB1, NEDBEH
  • Links
    NCBI Gene ID: 473
    neXtProt AC: NX_Q9P2R6
    UniProt: Q9P2R6

  • Chr Location
    1p36.23; chr1:8352404-8826226 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8101
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RERE
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    41 phenotypes from 3 alleles in 6 genetic backgrounds
    1 phenotype from multigenic genotypes
    6 images
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene display embryonic lethality with abnormalities in neural tube development, somite development, and in the embryonic heart. Mice homozygous for an ENU-induced allele exhibit narrow snouts, decreased body weight, renal agenesis and small eyes.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000010393 VEGA Gene Model | MGI Sequence Detail 340321 C57BL/6J ±  kb
    transcript OTTMUST00000024234 VEGA | MGI Sequence Detail 7728 Not Applicable  
    polypeptide OTTMUSP00000011146 VEGA | MGI Sequence Detail 1558 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      1872 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 184
      cDNA 184

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1915953, MGI:2140258, MGI:2140608, MGI:3577417
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 6
      Gene Ontology 5
      Phenotypes 19
    • Earliest
      J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
    • Latest
      J:246283 Fan Z, et al., A class of circadian long non-coding RNAs mark enhancers modulating long-range circadian gene regulation. Nucleic Acids Res. 2017 Jun 02;45(10):5720-5738

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    Funding Information
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory