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Rere
Gene Detail
 Symbol
Name
ID
Rere
arginine glutamic acid dipeptide (RE) repeats
MGI:2683486
Synonyms 1110033A15Rik, Atr2, atrophin-2, eye03, eyem03Jus, eyes3, mKIAA0458
Feature Type protein coding gene
Genetic Map
Chromosome 4
81.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:150281646-150621966 bp, + strand
From VEGA annotation of GRCm38

  340321 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8101  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Rere

Human
homologs
Human Homolog RERE, arginine-glutamic acid dipeptide (RE) repeats
NCBI Gene ID 473
neXtProt AC  NX_Q9P2R6
Human Synonyms  ARG, ARP, ATN1L, DNB1
Human Chr (Location)  1p36.23; chr1:8352404-8817640 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(228) : Chemically induced (ENU)(2) Gene trapped(223) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display embryonic lethality with abnormalities in neural tube development, somite development, and in the embryonic heart. Mice homozygous for an ENU-induced allele exhibit narrow snouts, decreased body weight, renal agenesis and small eyes.
 
Interactions
Rere interacts with 379 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process chromatin remodeling, multicellular organismal development, ...
Component histone deacetylase complex, nucleus
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (175)    Tissues (65)    Images (25)
Theiler Stages: 21, 23, 28
Assay TypeResults
RNA in situ 175
cDNA source data(184)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(185) cDNA(184) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000010393 (Evidence)
Ensembl Gene ModelENSMUSG00000039852 (Evidence)
Entrez Gene68703 (Evidence)
UniGene291274
DFCITC1605424, TC1643857, TC1656880
DoTSDT.101359566, DT.491044, DT.524935, DT.91324231
NIA Mouse Gene IndexU005140, U097639
Consensus CDS ProjectCCDS38979.1
International Mouse Knockout Project StatusRere
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010393 VEGA Gene Model | MGI Sequence Detail 340321 C57BL/6J ±  kb
transcript OTTMUST00000024234 VEGA | MGI Sequence Detail 7728 Not Applicable 
polypeptide OTTMUSP00000011146 VEGA | MGI Sequence Detail 1558 Not Applicable 

For the selected sequences
All sequences(106) RefSeq(52) UniProt(6)
Polymorphisms SNPs within 2kb(1924 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017993 Atrophin-1
InterPro IPR002951 Atrophin-like
InterPro IPR001025 Bromo adjacent homology (BAH) domain
InterPro IPR000949 ELM2 domain
InterPro IPR009057 Homeodomain-like
InterPro IPR017884 SANT domain
InterPro IPR001005 SANT/Myb domain
InterPro IPR000679 Zinc finger, GATA-type
Protein Ontology PR:000013890 arginine-glutamic acid dipeptide repeats protein
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:199403 Kim BJ, et al., An allelic series of mice reveals a role for RERE in the development of multiple organs affected in chromosome 1p36 deletions. PLoS One. 2013;8(2):e57460
All references(45)
Other
accession IDs
MGI:1915953, MGI:2140258, MGI:2140608, MGI:3577417

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory