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Serpinb3d
Gene Detail
 Symbol
Name
ID
Serpinb3d
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D
MGI:2683295
Feature Type protein coding gene
Genetic Map
Chromosome 1
50.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:107078167-107083506 bp, - strand
From VEGA annotation of GRCm38

  5340 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:130559  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee

Protein SuperFamily: serpin
Gene Tree: Serpinb3d

Human
homologs
Human Homolog SERPINB3, serpin peptidase inhibitor, clade B (ovalbumin), member 3
NCBI Gene ID 6317
neXtProt AC  NX_P29508
Human Synonyms  HsT1196, SCC, SCCA1, SCCA-1, SCCA-PD, T4-A
Human Chr (Location)  18q21.3; chr18:63655197-63661963 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process negative regulation of catalytic activity, negative regulation of endopeptidase activity, ...
Component extracellular region, extracellular vesicular exosome, ...
Function serine-type endopeptidase inhibitor activity, virus receptor activity
External Resources: FuncBase
Expression
cDNA source data(3)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(8) Genomic(5) cDNA(3)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000020997 (Evidence)
Ensembl Gene ModelENSMUSG00000058017 (Evidence)
Entrez Gene394252 (Evidence)
UniGene352392
DoTSDT.102553538
NIA Mouse Gene IndexU222842
Consensus CDS ProjectCCDS15215.1
International Mouse Knockout Project StatusSerpinb3d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020997 VEGA Gene Model | MGI Sequence Detail 5340 C57BL/6J ±  kb
transcript OTTMUST00000049643 VEGA | MGI Sequence Detail 1216 Not Applicable 
polypeptide OTTMUSP00000023034 VEGA | MGI Sequence Detail 387 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(91 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
References (Earliest) J:90618 Askew DJ, et al., The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases. Genomics. 2004 Jul;84(1):166-75
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory