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Serpinb3b
Gene Detail
 Symbol
Name
ID
Serpinb3b
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B
MGI:2683293
Synonyms Scca2-rs
Feature Type protein coding gene
Genetic Map
Chromosome 1
50.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:107153940-107161114 bp, - strand
From VEGA annotation of GRCm38

  7175 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:131278  Vertebrate Homology Class
2 mouse

Protein SuperFamily: serpin
Gene Tree: Serpinb3b

Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process negative regulation of endopeptidase activity, regulation of proteolysis
Component extracellular region
Function cysteine-type endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (31)    Tissues (31)    Images (3)
Theiler Stages: 17, 21
Assay TypeResults
RNA in situ 31
cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(8) Genomic(4) cDNA(4)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000021003 (Evidence)
Ensembl Gene ModelENSMUSG00000073602 (Evidence)
Entrez Gene383548 (Evidence)
UniGene483991
DoTSDT.55245641
NIA Mouse Gene IndexU021666
Consensus CDS ProjectCCDS15216.1
International Mouse Knockout Project StatusSerpinb3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021003 VEGA Gene Model | MGI Sequence Detail 7175 C57BL/6J ±  kb
transcript OTTMUST00000049655 VEGA | MGI Sequence Detail 1653 Not Applicable 
polypeptide OTTMUSP00000023041 VEGA | MGI Sequence Detail 387 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(94 from dbSNP Build 137)    SNPs within 2kb including multiple locations(102)
Protein-related
information
ResourceIDDescription
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
References (Earliest) J:90618 Askew DJ, et al., The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases. Genomics. 2004 Jul;84(1):166-75
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(21)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory