Serpinb3b
Gene Detail

Symbol Name ID

Serpinb3b serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B MGI:2683293

Synonyms

Scca2-rs

Feature Type

protein coding gene

Genetic Map

Chromosome 1

50.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:107153940-107161114 bp, - strand From VEGA annotation of GRCm38   7175 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:131278  Vertebrate Homology Class
2 mouse

Protein SuperFamily: serpin
Gene Tree: Serpinb3b

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	negative regulation of endopeptidase activity, regulation of proteolysis
Component	extracellular region
Function	cysteine-type endopeptidase inhibitor activity, serine-type endopeptidase inhibitor activity

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (31)    Tissues (31)    Images (3)
Theiler Stages: 17, 21

Assay Type	Results
RNA in situ	31

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(8) Genomic(4) cDNA(4)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000021003 (Evidence)
Ensembl Gene Model	ENSMUSG00000073602 (Evidence)
Entrez Gene	383548 (Evidence)
UniGene	483991
DoTS	DT.55245641
NIA Mouse Gene Index	U021666
Consensus CDS Project	CCDS15216.1
International Mouse Knockout Project Status	Serpinb3b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021003	VEGA Gene Model | MGI Sequence Detail	7175	C57BL/6J
transcript	OTTMUST00000049655	VEGA | MGI Sequence Detail	1653	Not Applicable
polypeptide	OTTMUSP00000023041	VEGA | MGI Sequence Detail	387	Not Applicable

All sequences(21) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(74 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023796	Serpin domain
InterPro	IPR000215	Serpin family

References

(Earliest) J:90618 Askew DJ, et al., The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases. Genomics. 2004 Jul;84(1):166-75
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(21)