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Serpinb3b Gene Detail
Summary
  • Symbol
    Serpinb3b
  • Name
    serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B
  • Synonyms
    Scca2-rs
  • Feature Type
    protein coding gene
  • IDs
    MGI:2683293
    NCBI Gene: 383548
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr1:107153961-107161114 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 50.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    90 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2683293
protein coding gene Chr1:107153940-107278361 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016378
protein coding gene Chr1:109364657-109493887 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0016317
protein coding gene Chr1:105764969-105771193 (-)
C3H/HeJ MGP_C3HHeJ_G0016145
protein coding gene Chr1:108869460-109019348 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016777
protein coding gene Chr1:113522258-113668431 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014494
protein coding gene Chr1:99744825-99751997 (-)
CAST/EiJ MGP_CASTEiJ_G0015728
protein coding gene Chr1:107885070-107948255 (-)
CBA/J MGP_CBAJ_G0016118
protein coding gene Chr1:117542135-117554531 (-)
DBA/2J MGP_DBA2J_G0016223
protein coding gene Chr1:104719289-104727522 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0016297
protein coding gene Chr1:110658671-110784219 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016250
protein coding gene Chr1:121954896-121977369 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0015299
protein coding gene Chr1:107041730-107048381 (-)
WSB/EiJ MGP_WSBEiJ_G0015789
protein coding gene Chr1:108484105-108487964 (-)



Homology
more
  • Human Ortholog
    SERPINB3, serpin family B member 3
  • Vertebrate Orthologs
    2
  • Human Ortholog
    SERPINB3, serpin family B member 3
    Orthology source: HGNC
  • Synonyms
    HsT1196, SCC, SCCA1, SCCA-1, SCCA-PD, SSCA1, T4-A
  • Links
    NCBI Gene ID: 6317
    neXtProt AC: NX_P29508
    UniProt: P29508

  • Chr Location
    18q21.33; chr18:63655197-63661963 (-)  GRCh38.p7

  • Human Ortholog
    SERPINB4, serpin family B member 4
    Orthology source: HGNC
  • Synonyms
    LEUPIN, PI11, SCCA1, SCCA2, SCCA-2
  • Links
    NCBI Gene ID: 6318
    neXtProt AC: NX_P48594
    UniProt: P48594

  • Chr Location
    18q21.33; chr18:63637259-63644319 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 383548 NCBI Gene Model | MGI Sequence Detail 7154 C57BL/6J ±  kb
transcript NM_198680 RefSeq | MGI Sequence Detail 1632 C57BL/6  
polypeptide NP_941373 RefSeq | MGI Sequence Detail 387 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    Genomic 4
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:273177 Gerber H, et al., The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease. Acta Neuropathol Commun. 2019 Jan 31;7(1):13

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory