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Tmem39b Gene Detail
Summary
  • Symbol
    Tmem39b
  • Name
    transmembrane protein 39b
  • Synonyms
    6330509E05Rik, MGC:59407
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682939
    NCBI Gene: 230770
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129570148-129590631 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 63.31 cM, cytoband D2.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    220 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2682939
 protein coding gene Chr4:129570145-129595850 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028837
 protein coding gene Chr4:131618547-131640030 (-)
A/J MGP_AJ_G0028796
 protein coding gene Chr4:126356841-126378048 (-)
AKR/J MGP_AKRJ_G0028749
 protein coding gene Chr4:129880797-129902955 (-)
BALB/cJ MGP_BALBcJ_G0028819
 protein coding gene Chr4:126963310-126983996 (-)
C3H/HeJ MGP_C3HHeJ_G0028533
 protein coding gene Chr4:129942755-129963445 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029261
 protein coding gene Chr4:136561669-136591511 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026533
 protein coding gene Chr4:119486909-119508926 (-)
CAST/EiJ MGP_CASTEiJ_G0027965
 protein coding gene Chr4:128122648-128148210 (-)
CBA/J MGP_CBAJ_G0028499
 protein coding gene Chr4:139984999-140012712 (-)
DBA/2J MGP_DBA2J_G0028648
 protein coding gene Chr4:126792253-126812329 (-)
FVB/NJ MGP_FVBNJ_G0028615
 protein coding gene Chr4:125549008-125569186 (-)
LP/J MGP_LPJ_G0028749
 protein coding gene Chr4:131923395-131952200 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028641
 protein coding gene Chr4:144762775-144787237 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029299
 protein coding gene Chr4:130249445-130272307 (-)
PWK/PhJ MGP_PWKPhJ_G0027687
 protein coding gene Chr4:123392637-123413456 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027513
 protein coding gene Chr4:126118832-126140697 (-)
WSB/EiJ MGP_WSBEiJ_G0028046
 protein coding gene Chr4:130377564-130400041 (-)



Homology
more
  • Human Ortholog
    TMEM39B, transmembrane protein 39B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM39B, transmembrane protein 39B
  • Links
    NCBI Gene ID: 55116
    UniProt: Q9GZU3

  • Chr Location
    1p35.2; chr1:32072031-32102866 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    4 involving Tmem39b
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    25 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    31
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053730 Ensembl Gene Model | MGI Sequence Detail 20484 C57BL/6J ±  kb
transcript ENSMUST00000102588 Ensembl | MGI Sequence Detail 1810 Not Applicable  
polypeptide ENSMUSP00000099648 Ensembl | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 31

    Microarray probesets 1
Other
Accession IDs
less
MGI:1923394
References
more
  • Summaries
    All 33
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory