Tmem39b Gene Detail

Summary

• Symbol
  Tmem39b
• Name
  transmembrane protein 39b
• Synonyms
  6330509E05Rik, MGC:59407

• Feature Type
  protein coding gene
• IDs
  MGI:2682939
  NCBI Gene: 230770

Location & Maps

• Sequence Map
  Chr4:129676355-129696838 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    20484 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 63.31 cM, cytoband D2.3
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  TMEM39B, transmembrane protein 39B

• Vertebrate Orthologs
  10

• Human Ortholog
  TMEM39B, transmembrane protein 39B
  Orthology source: HomoloGene, HGNC
• Links
  HGNC:25510

  NCBI Gene ID: 55116

  neXtProt AC: NX_Q9GZU3

  UniProt: Q9GZU3

  
  
• Chr Location
  1p35.2; chr1:32072031-32102866 (+)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 23069
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  
• HCOP
  human homology predictions: TMEM39B
• Gene Tree
  Tmem39b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  11 phenotype references
  

• All Mutations and Alleles
  8
• Chemically induced (other)
  2
• Gene trapped
  1
• Radiation induced
  1
• Targeted
  4
• Genomic Mutations
  4 involving Tmem39b
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  17 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

• External Resources
  FuncBase

Expression

• cDNA Data
  30

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase tmem39b
  ZFIN tmem39b

Interactions

• Tmem39b interacts with 248 markers (Mir1a-1, Mir1a-2, Mir7-1, ...) View All

Sequences &
Gene Models

• All Sequences
  37
• RefSeq
  8
• UniProt
  4
• CCDS
  CCDS18702.1
• UniGene
  257157

• VEGA
  OTTMUSG00000009517 (Evidence)
• Ensembl
  ENSMUSG00000053730 (Evidence)
• NCBI Gene
  230770 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000009517	VEGA Gene Model | MGI Sequence Detail	20484	C57BL/6J
transcript	OTTMUST00000021763	VEGA | MGI Sequence Detail	1810	Not Applicable
polypeptide	OTTMUSP00000009928	VEGA | MGI Sequence Detail	492	Not Applicable

Polymorphisms

• SNPs within 2kb
  202 from dbSNP Build 142

Protein
Information

• UniProt
  4 Sequences
• Protein Ontology
  PR:000031382 transmembrane protein 39B
  (term hierarchy)
• InterPro Domains
  IPR019397 Uncharacterised protein family TMEM39

Molecular
Reagents

• All nucleic 30

  cDNA 30

  
  

  Microarray probesets 1

Other
Accession IDs

MGI:1923394

References

• Summaries
  All 29

  Gene Ontology 1

  Phenotypes 11
• Earliest
  J:23094 Davisson MT, New chromosome aberrations. Mouse News Lett. 1988;80:166
• Latest
  J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42