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Smg7 Gene Detail
Summary
  • Symbol
    Smg7
  • Name
    Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
  • Synonyms
    9430023P16Rik, mKIAA0250
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682334
    NCBI Gene: 226517
  • Gene Overview
    MyGene.info: SMG7
Location & Maps
more
  • Sequence Map
    Chr1:152836995-152902646 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      65652 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 65.07 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SMG7, SMG7, nonsense mediated mRNA decay factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SMG7, SMG7, nonsense mediated mRNA decay factor
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C1orf16, EST1C, SGA56M
  • Links
    NCBI Gene ID: 9887
    neXtProt AC: NX_Q92540

  • Chr Location
    1q25; chr1:183472371-183554193 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 32235
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: SMG7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    71
  • Chemically induced (other)
    2
  • Gene trapped
    69
  • Genomic Mutations
    2 involving Smg7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049697 VEGA Gene Model | MGI Sequence Detail 65652 C57BL/6J ±  kb
transcript OTTMUST00000126592 VEGA | MGI Sequence Detail 5792 Not Applicable  
polypeptide OTTMUSP00000068435 VEGA | MGI Sequence Detail 1146 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    381 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000015286 protein SMG7
  • InterPro Domains
    IPR018834 DNA/RNA-binding domain, Est1-type
    IPR019458 Telomerase activating protein Est1
    IPR011990 Tetratricopeptide-like helical domain
Molecular
Reagents
less
  • All nucleic 104
    cDNA 104

    Microarray probesets 1
References
more
  • Summaries
    All 27
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory