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Smg7 Gene Detail
Summary
  • Symbol
    Smg7
  • Name
    Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
  • Synonyms
    9430023P16Rik, mKIAA0250
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682334
    NCBI Gene: 226517
  • Gene Overview
    MyGene.info: SMG7
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:152836995-152902646 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 65.07 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    381 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2682334
protein coding gene Chr1:152836995-152902684 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016592
protein coding gene Chr1:157616778-157684107 (-)
A/J MGP_AJ_G0016574
protein coding gene Chr1:151264025-151330422 (-)
AKR/J MGP_AKRJ_G0016539
protein coding gene Chr1:155940292-156011808 (-)
BALB/cJ MGP_BALBcJ_G0016534
protein coding gene Chr1:151838079-151904339 (-)
C3H/HeJ MGP_C3HHeJ_G0016359
protein coding gene Chr1:156043112-156111032 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016995
protein coding gene Chr1:163061978-163133268 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014704
protein coding gene Chr1:143582305-143646143 (-)
CAST/EiJ MGP_CASTEiJ_G0015938
protein coding gene Chr1:155547118-155617505 (-)
CBA/J MGP_CBAJ_G0016333
protein coding gene Chr1:168804795-168877042 (-)
DBA/2J MGP_DBA2J_G0016439
protein coding gene Chr1:150278968-150345428 (-)
FVB/NJ MGP_FVBNJ_G0016437
protein coding gene Chr1:148767627-148833138 (-)
LP/J MGP_LPJ_G0016510
protein coding gene Chr1:158728971-158800594 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016463
protein coding gene Chr1:176448211-176519893 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017031
protein coding gene Chr1:155717959-155786087 (-)
PWK/PhJ MGP_PWKPhJ_G0015724
protein coding gene Chr1:149296144-149362971 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015511
protein coding gene Chr1:154523293-154595547 (-)
WSB/EiJ MGP_WSBEiJ_G0016001
protein coding gene Chr1:155781343-155852081 (-)



Homology
more
  • Human Ortholog
    SMG7, SMG7, nonsense mediated mRNA decay factor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SMG7, SMG7, nonsense mediated mRNA decay factor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1orf16, EST1C, SGA56M
  • Links
    NCBI Gene ID: 9887
    neXtProt AC: NX_Q92540
    UniProt: Q92540

  • Chr Location
    1q25.3; chr1:183471962-183554193 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 32235
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SMG7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042772 Ensembl Gene Model | MGI Sequence Detail 65652 C57BL/6J ±  kb
transcript ENSMUST00000043560 Ensembl | MGI Sequence Detail 5792 Not Applicable  
polypeptide ENSMUSP00000041241 Ensembl | MGI Sequence Detail 1146 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 106
    cDNA 106

    Microarray probesets 1
References
more
  • Summaries
    All 29
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory