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Zfp395 Gene Detail
Summary
  • Symbol
    Zfp395
  • Name
    zinc finger protein 395
  • Synonyms
    BC027382, LOC380912, MGC:60757
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682318
    NCBI Gene: 380912
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:65358676-65398930 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 34.32 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    226 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2682318
protein coding gene Chr14:65358389-65398930 (.)
129S1/SvImJ MGP_129S1SvImJ_G0021479
protein coding gene Chr14:59958006-60000793 (+)
A/J MGP_AJ_G0021438
protein coding gene Chr14:58573581-58614466 (+)
AKR/J MGP_AKRJ_G0021414
protein coding gene Chr14:60607496-60648953 (+)
BALB/cJ MGP_BALBcJ_G0021444
protein coding gene Chr14:58509671-58550232 (+)
C3H/HeJ MGP_C3HHeJ_G0021221
protein coding gene Chr14:60253717-60294842 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021883
protein coding gene Chr14:62738825-62779076 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019423
protein coding gene Chr14:56503910-56544528 (+)
CAST/EiJ MGP_CASTEiJ_G0020738
protein coding gene Chr14:56732933-56776247 (+)
CBA/J MGP_CBAJ_G0021188
protein coding gene Chr14:64631426-64671522 (+)
DBA/2J MGP_DBA2J_G0021311
protein coding gene Chr14:58222543-58264021 (+)
FVB/NJ MGP_FVBNJ_G0021290
protein coding gene Chr14:57623187-57663544 (+)
LP/J MGP_LPJ_G0021386
protein coding gene Chr14:60996699-61039586 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021319
protein coding gene Chr14:63740662-63781077 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021906
protein coding gene Chr14:59787401-59828037 (+)
PWK/PhJ MGP_PWKPhJ_G0020482
protein coding gene Chr14:54930131-54971484 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020315
protein coding gene Chr14:55763615-55790441 (+)
WSB/EiJ MGP_WSBEiJ_G0020791
protein coding gene Chr14:60099959-60141864 (+)



Homology
more
  • Human Ortholog
    ZNF395, zinc finger protein 395
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZNF395, zinc finger protein 395
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HDBP2, HDBP-2, HDRF-2, PBF, PRF1, PRF-1, Si-1-8-14
  • Links
    NCBI Gene ID: 55893
    neXtProt AC: NX_Q9H8N7
    UniProt: Q9H8N7

  • Chr Location
    8p21.1; chr8:28345585-28386460 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10255
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ZNF395
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    59
  • Chemically induced (other)
    1
  • Gene trapped
    56
  • Targeted
    2
  • Genomic Mutations
    1 involving Zfp395
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380912 NCBI Gene Model | MGI Sequence Detail 40255 C57BL/6J ±  kb
transcript NM_199029 RefSeq | MGI Sequence Detail 4229 C57BL/6  
polypeptide NP_950194 RefSeq | MGI Sequence Detail 508 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR031940 Domain of unknown function DUF4772
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 4
Other
Accession IDs
less
MGI:2685756, MGI:3039574
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:197686 Shang Y, et al., Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-beta-TAK1-dependent mechanism. PLoS Biol. 2013;11(4):e1001527

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory