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Zfp395 Gene Detail
Summary
  • Symbol
    Zfp395
  • Name
    zinc finger protein 395
  • Synonyms
    BC027382, LOC380912, MGC:60757
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682318
    NCBI Gene: 380912
Location & Maps
more
  • Sequence Map
    Chr14:65358676-65398930 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      40255 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 34.32 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ZNF395, zinc finger protein 395
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZNF395, zinc finger protein 395
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HDBP2, HDBP-2, HDRF-2, PBF, PRF1, PRF-1, Si-1-8-14
  • Links
    NCBI Gene ID: 55893
    neXtProt AC: NX_Q9H8N7

  • Chr Location
    8p21.1; chr8:28345585-28386460 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10255
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ZNF395
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    59
  • Chemically induced (other)
    1
  • Gene trapped
    56
  • Targeted
    2
  • Genomic Mutations
    1 involving Zfp395
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 380912 NCBI Gene Model | MGI Sequence Detail 40255 C57BL/6J ±  kb
transcript NM_199029 RefSeq | MGI Sequence Detail 4229 C57BL/6  
polypeptide NP_950194 RefSeq | MGI Sequence Detail 508 C57BL/6  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    226 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR031940 Domain of unknown function DUF4772
    IPR007087 Zinc finger, C2H2
Molecular
Reagents
less
  • All nucleic 76
    cDNA 76

    Microarray probesets 4
Other
Accession IDs
less
MGI:2685756, MGI:3039574
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:197686 Shang Y, et al., Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-beta-TAK1-dependent mechanism. PLoS Biol. 2013;11(4):e1001527

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/17/2017
MGI 6.07
The Jackson Laboratory