Zc3h4 MGI Mouse Gene Detail - MGI:2682314 - zinc finger CCCH-type containing 4

Zc3h4 Gene Detail

Symbol

Zc3h4
Name

zinc finger CCCH-type containing 4
Synonyms

Bwq1, Kiaa1064-hp, LOC330474, MGC:67629, mKIAA1064

Feature Type

protein coding gene
IDs

MGI:2682314
NCBI Gene: 330474
Alliance

gene page

Sequence Map

Chr7:16401207-16437696 bp, + strand
From VEGA annotation of GRCm38

Mouse Genome Browser
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Sequence

36490 bp ± kb flank
Genome Browsers

VEGA | Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 9.03 cM
Mapping Data

7 experiments

Human Ortholog

ZC3H4, zinc finger CCCH-type containing 4

Vertebrate Orthologs

8

Human Ortholog

ZC3H4, zinc finger CCCH-type containing 4
Orthology source: HomoloGene, HGNC
Synonyms

C19orf7
Links

HGNC:17808

NCBI Gene ID: 23211

neXtProt AC: NX_Q9UPT8

UniProt: Q9UPT8
Chr Location

19q13.32; chr19:47064187-47114436 (-) GRCh38.p7

HomoloGene

Vertebrate Homology Class 87150
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 frog, western clawed;1 macaque, rhesus
HCOP

human homology predictions: ZC3H4
Gene Tree

Zc3h4

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
1 phenotype from multigenic genotypes
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

191
Gene trapped

188
QTL

2
Targeted

1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

163 strains or lines available

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All GO Annotations

3
GO References

3

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	receptor	receptor binding	RNA binding	transcription	transferase	transporter

Biological Process

nucleic acid-templated transcription	carbohydrate derivative metabolism	cell death	cell differentiation	cell proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

13
Tissues

11
cDNA Data

8
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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Zc3h4 interacts with 323 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

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All Sequences

53
RefSeq

20
UniProt

6
CCDS

CCDS52040.1

			Length	Strain/Species	Flank
genomic	OTTMUSG00000060585	VEGA Gene Model \| MGI Sequence Detail	36490	C57BL/6J	± kb
transcript	OTTMUST00000148217	VEGA \| MGI Sequence Detail	6039	Not Applicable
polypeptide	OTTMUSP00000077080	VEGA \| MGI Sequence Detail	1255	Not Applicable

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SNPs within 2kb

199 from dbSNP Build 142

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UniProt

6 Sequences
Protein Ontology

PR:000031210 zinc finger CCCH domain-containing protein 4

(term hierarchy)
InterPro Domains

IPR000571 Zinc finger, CCCH-type

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All nucleic 11

Genomic 2

cDNA 9

Microarray probesets 1

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MGI:1298203, MGI:2389001, MGI:2685614

Summaries

All 36

Developmental Gene Expression 3

Gene Ontology 3

Phenotypes 11
Earliest

J:48704 Suto J, et al., Genetics of obesity in KK mouse and effects of A(y) allele on quantitative regulation. Mamm Genome. 1998 Jul;9(7):506-10
Latest

J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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