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Chil6 Gene Detail
Summary
  • Symbol
    Chil6
  • Name
    chitinase-like 6
  • Synonyms
    BC051070, BYm, MGC:58999
  • Feature Type
    protein coding gene
  • IDs
    MGI:2682303
    NCBI Gene: 229688
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:106294700-106313498 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 46.49 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    100 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2682303
protein coding gene Chr3:106294700-106313517 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027732
protein coding gene Chr3:107854594-107873383 (-)
A/J MGP_AJ_G0027692
protein coding gene Chr3:104417161-104436388 (-)
AKR/J MGP_AKRJ_G0027657
protein coding gene Chr3:106976713-106996078 (-)
BALB/cJ MGP_BALBcJ_G0027704
protein coding gene Chr3:104109050-104127841 (-)
C3H/HeJ MGP_C3HHeJ_G0027434
protein coding gene Chr3:107310769-107329535 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028148
protein coding gene Chr3:111859958-111878817 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025486
protein coding gene Chr3:100610430-100622769 (-)
CAST/EiJ MGP_CASTEiJ_G0026890
protein coding gene Chr3:106685064-106705586 (-)
CBA/J MGP_CBAJ_G0027409
protein coding gene Chr3:115656213-115674992 (-)
DBA/2J MGP_DBA2J_G0027551
protein coding gene Chr3:103623125-103639593 (-)
FVB/NJ MGP_FVBNJ_G0027519
protein coding gene Chr3:101541792-101560560 (-)
LP/J MGP_LPJ_G0027658
protein coding gene Chr3:109225561-109242429 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027549
protein coding gene Chr3:121729826-121755288 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028203
protein coding gene Chr3:106549116-106568877 (-)
PWK/PhJ MGP_PWKPhJ_G0026616
protein coding gene Chr3:103358445-103379969 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026436
protein coding gene Chr3:104547758-104684468 (-)
WSB/EiJ MGP_WSBEiJ_G0026970
protein coding gene Chr3:107112869-107130928 (-)



Homology
more
  • Human Ortholog
    CHIA, chitinase acidic
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHIA, chitinase acidic
  • Synonyms
    AMCASE, CHIT2, TSA1902
  • Links
    NCBI Gene ID: 27159
    neXtProt AC: NX_Q9BZP6
    UniProt: Q9BZP6

  • Chr Location
    1p13.2; chr1:111290851-111320566 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human CHIA associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027902 Ensembl Gene Model | MGI Sequence Detail 18799 C57BL/6J ±  kb
transcript ENSMUST00000029510 Ensembl | MGI Sequence Detail 1668 Not Applicable  
polypeptide ENSMUSP00000029510 Ensembl | MGI Sequence Detail 440 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR011583 Chitinase II
    IPR029070 Chitinase insertion domain superfamily
    IPR001223 Glycoside hydrolase family 18, catalytic domain
    IPR017853 Glycoside hydrolase superfamily
Molecular
Reagents
less
  • All nucleic 3
    cDNA 2
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory