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Cep135
Gene Detail
Symbol

Name
ID
Cep135
centrosomal protein 135
MGI:2681869
Synonyms
Cep4, LOC381644, MGC:86039
Feature Type
protein coding gene
Genetic Map
Chromosome 5
41.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:76588698-76646466 bp, + strand
From VEGA annotation of GRCm38

  57769 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45709  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CEP135
Gene Tree: Cep135

Human
homologs
CEP135, centrosomal protein 135kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9662
neXtProt AC: NX_Q66GS9

Human Synonyms: CEP4, KIAA0635, MCPH8

Human Chr (Location): 4q12; chr4:55948808-56033363 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CEP135

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cep135 interacts with 320 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process centriole-centriole cohesion, centriole replication
Component centriole, centrosome, ...
Function protein C-terminus binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(23)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase cep135    NEW 
Molecular
reagents
All nucleic(24) cDNA(24)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000026443 (Evidence)
Ensembl Gene Model ENSMUSG00000036403 (Evidence)
Entrez Gene 381644 (Evidence)
UniGene 332452
DFCI TC1583247
DoTS DT.101154856, DT.101210779
NIA Mouse Gene Index U005706
Consensus CDS Project CCDS19365.1
International Mouse Phenotyping Consortium Status Cep135
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026443 VEGA Gene Model | MGI Sequence Detail 57769 C57BL/6J ±  kb
transcript OTTMUST00000065403 VEGA | MGI Sequence Detail 5537 Not Applicable 
polypeptide OTTMUSP00000032596 VEGA | MGI Sequence Detail 1140 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(13) UniProt(2)
Polymorphisms
SNPs within 2kb(342 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026732 Centrosomal protein of 135kDa
Protein Ontology PR:000005341 centrosomal protein of 135 kDa
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:162627 Kinzel D, et al., Pitchfork regulates primary cilia disassembly and left-right asymmetry. Dev Cell. 2010 Jul 20;19(1):66-77
All references(29)
Other
accession IDs
MGI:2685890

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory