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Cep135
Gene Detail
 Symbol
Name
ID
Cep135
centrosomal protein 135
MGI:2681869
Synonyms Cep4, LOC381644, MGC:86039
Feature Type protein coding gene
Genetic Map
Chromosome 5
41.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:76588698-76646466 bp, + strand
From VEGA annotation of GRCm38

  57769 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45709  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Cep135

Human
homologs
Human Homolog CEP135, centrosomal protein 135kDa
NCBI Gene ID 9662
neXtProt AC  NX_Q66GS9
Human Synonyms  CEP4, KIAA0635, MCPH8
Human Chr (Location)  4q12; chr4:55948808-56033363 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human CEP135
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cep135 interacts with 320 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process centriole-centriole cohesion, centriole replication
Component centriole, centrosome, ...
Function protein C-terminus binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(23)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(24) cDNA(24)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026443 (Evidence)
Ensembl Gene ModelENSMUSG00000036403 (Evidence)
Entrez Gene381644 (Evidence)
UniGene332452
DFCITC1583247
DoTSDT.101154856, DT.101210779
NIA Mouse Gene IndexU005706
Consensus CDS ProjectCCDS19365.1
International Mouse Knockout Project StatusCep135
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026443 VEGA Gene Model | MGI Sequence Detail 57769 C57BL/6J ±  kb
transcript OTTMUST00000065403 VEGA | MGI Sequence Detail 5537 Not Applicable 
polypeptide OTTMUSP00000032596 VEGA | MGI Sequence Detail 1140 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(16) UniProt(2)
Polymorphisms SNPs within 2kb(342 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026732 Centrosomal protein of 135kDa
Protein Ontology PR:000005341 centrosomal protein of 135 kDa
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:162627 Kinzel D, et al., Pitchfork regulates primary cilia disassembly and left-right asymmetry. Dev Cell. 2010 Jul 20;19(1):66-77
All references(30)
Other
accession IDs
MGI:2685890

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory