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Tbc1d22b Gene Detail
Summary
  • Symbol
    Tbc1d22b
  • Name
    TBC1 domain family, member 22B
  • Synonyms
    MGC:31516, MGC:61359
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681867
    NCBI Gene: 381085
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:29549788-29606894 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 15.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    370 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681867
protein coding gene Chr17:29549788-29606895 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023468
protein coding gene Chr17:29095202-29152205 (+)
A/J MGP_AJ_G0023426
protein coding gene Chr17:28119534-28177688 (+)
AKR/J MGP_AKRJ_G0023391
protein coding gene Chr17:28341997-28400466 (+)
BALB/cJ MGP_BALBcJ_G0023431
protein coding gene Chr17:28355186-28412668 (+)
C3H/HeJ MGP_C3HHeJ_G0023192
protein coding gene Chr17:28722967-28782061 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023873
protein coding gene Chr17:30232157-30292051 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021347
protein coding gene Chr17:25418373-25478753 (+)
CAST/EiJ MGP_CASTEiJ_G0022693
protein coding gene Chr17:28703083-28761532 (+)
CBA/J MGP_CBAJ_G0023167
protein coding gene Chr17:31386680-31448509 (+)
DBA/2J MGP_DBA2J_G0023297
protein coding gene Chr17:27617653-27674428 (+)
FVB/NJ MGP_FVBNJ_G0023267
protein coding gene Chr17:27457441-27515785 (+)
LP/J MGP_LPJ_G0023375
protein coding gene Chr17:29352778-29409714 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023285
protein coding gene Chr17:30702666-30760999 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023915
protein coding gene Chr17:28805419-28863193 (+)
PWK/PhJ MGP_PWKPhJ_G0022443
protein coding gene Chr17:26462448-26520978 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022261
protein coding gene Chr17:26781484-26839636 (+)
WSB/EiJ MGP_WSBEiJ_G0022755
protein coding gene Chr17:28773485-28832014 (+)



Homology
more
  • Human Ortholog
    TBC1D22B, TBC1 domain family member 22B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TBC1D22B, TBC1 domain family member 22B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C6orf197
  • Links
    NCBI Gene ID: 55633
    neXtProt AC: NX_Q9NU19
    UniProt: Q9NU19

  • Chr Location
    6p21.2; chr6:37257704-37332970 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381085 NCBI Gene Model | MGI Sequence Detail 57107 C57BL/6J ±  kb
transcript NM_198647 RefSeq | MGI Sequence Detail 3505 FVB/N  
polypeptide NP_941049 RefSeq | MGI Sequence Detail 505 FVB/N  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR000195 Rab-GTPase-TBC domain
    IPR035969 Rab-GTPase-TBC domain superfamily
Molecular
Reagents
less
  • All nucleic 44
    cDNA 44

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory