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Efcab12 Gene Detail
Summary
  • Symbol
    Efcab12
  • Name
    EF-hand calcium binding domain 12
  • Synonyms
    BC060267, MGC:69711
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681834
    NCBI Gene: 212516
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:115810729-115838412 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 53.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    159 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681834
protein coding gene Chr6:115810729-115838577 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031156
protein coding gene Chr6:118460678-118482806 (-)
A/J MGP_AJ_G0031126
protein coding gene Chr6:113911184-113934459 (-)
AKR/J MGP_AKRJ_G0031056
protein coding gene Chr6:116970435-116992384 (-)
BALB/cJ MGP_BALBcJ_G0031136
protein coding gene Chr6:113717958-113740574 (-)
C3H/HeJ MGP_C3HHeJ_G0030572
protein coding gene Chr6:67308810-67331682 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031595
protein coding gene Chr6:121475505-121505807 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028759
protein coding gene Chr6:110914690-110937124 (-)
CAST/EiJ MGP_CASTEiJ_G0030243
protein coding gene Chr6:117341026-117365794 (-)
CBA/J MGP_CBAJ_G0030822
protein coding gene Chr6:126252569-126274477 (-)
DBA/2J MGP_DBA2J_G0030976
protein coding gene Chr6:112833302-112855916 (-)
FVB/NJ MGP_FVBNJ_G0030929
protein coding gene Chr6:112012745-112034979 (-)
LP/J MGP_LPJ_G0031055
protein coding gene Chr6:118471024-118493131 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030964
protein coding gene Chr6:130420525-130442671 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031623
protein coding gene Chr6:116992080-117015141 (-)
PWK/PhJ MGP_PWKPhJ_G0029959
protein coding gene Chr6:111848671-111871313 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029787
protein coding gene Chr6:115708518-115732238 (-)
WSB/EiJ MGP_WSBEiJ_G0030327
protein coding gene Chr6:117255273-117278779 (-)



Homology
more
  • Human Ortholog
    EFCAB12, EF-hand calcium binding domain 12
  • Vertebrate Orthologs
    9
  • Human Ortholog
    EFCAB12, EF-hand calcium binding domain 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C3orf25
  • Links
    NCBI Gene ID: 90288
    neXtProt AC: NX_Q6NXP0
    UniProt: Q6NXP0

  • Chr Location
    3q21.3; chr3:129401321-129428651 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    12
  • Endonuclease-mediated
    1
  • Gene trapped
    9
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Efcab12
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030321 Ensembl Gene Model | MGI Sequence Detail 27684 C57BL/6J ±  kb
transcript ENSMUST00000184428 Ensembl | MGI Sequence Detail 2384 Not Applicable  
polypeptide ENSMUSP00000139144 Ensembl | MGI Sequence Detail 673 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR042847 EF-hand calcium-binding domain-containing protein 12
    IPR002048 EF-hand domain
    IPR011992 EF-hand domain pair
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 2
Other
Accession IDs
less
MGI:2141728
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Phenotypes 8
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory