Prss34
Gene Detail

Symbol Name ID

Prss34 protease, serine, 34 MGI:2681414

Synonyms

mast cell protease 11, mMcp-11

Feature Type

protein coding gene

Genetic Map

Chromosome 17

12.53 cM, cytoband A3.3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr17:25298394-25300161 bp, + strand From NCBI annotation of GRCm38   1768 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:55542  Vertebrate Homology Class
1 mouse; 1 rat; 2 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: trypsin
Gene Tree: Prss34

Alleles and phenotypes

All alleles(2) : Targeted(2)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan, proteolysis
Component	extracellular matrix, extracellular space
Function	glycosaminoglycan binding, heparin binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (21)    Tissues (21)    Images (3)
Theiler Stages: 10, 18, 23, 24, 25, 28

Assay Type	Results
Immunohistochemistry	1
RT-PCR	20

cDNA source data(3)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(3) Primer pair(1) Other(1)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000056399 (Evidence)
Entrez Gene	328780 (Evidence)
UniGene	127166
DFCI	TC1588381
DoTS	DT.101362832
NIA Mouse Gene Index	U017670
Consensus CDS Project	CCDS28514.1
International Mouse Knockout Project Status	Prss34

Sequences

Length	Strain/Species
genomic	328780	NCBI Gene Model | MGI Sequence Detail	1768	C57BL/6J
transcript	NM_178372	RefSeq | MGI Sequence Detail	1216	BALB/c
polypeptide	NP_848459	RefSeq | MGI Sequence Detail	318	BALB/c

All sequences(14) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(29 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site

References

(Earliest) J:86752 Wong GW, et al., Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns. J Biol Chem. 2004 Jan 23;279(4):2438-52
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(19)