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Pigl
Gene Detail
Symbol

Name
ID
Pigl
phosphatidylinositol glycan anchor biosynthesis, class L
MGI:2681271
Synonyms
LOC327942
Feature Type
protein coding gene
Genetic Map
Chromosome 11
38.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:62458460-62514417 bp, + strand
From VEGA annotation of GRCm38

  55958 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3159  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pigl

Human
homologs
Human Homolog PIGL, phosphatidylinositol glycan anchor biosynthesis, class L
NCBI Gene ID 9487
neXtProt AC  NX_Q9Y2B2
Human Synonyms  CHIME
Human Chr (Location)  17p12-p11.2; chr17:16217195-16326784 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PIGL
Mutations,
alleles, and
phenotypes
All mutations/alleles(375) : Gene trapped(371) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pigl interacts with 132 markers (Mir7-1, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(2)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(3) Genomic(1) cDNA(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000005858 (Evidence)
Ensembl Gene ModelENSMUSG00000014245 (Evidence)
Entrez Gene327942 (Evidence)
DFCITC1587825, TC1586701, TC1605710
NIA Mouse Gene IndexU012735
EC3.5.1.89
Consensus CDS ProjectCCDS24824.1
International Mouse Knockout Project StatusPigl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005858 VEGA Gene Model | MGI Sequence Detail 55958 C57BL/6J ±  kb
transcript OTTMUST00000013037 VEGA | MGI Sequence Detail 2174 Not Applicable 
polypeptide OTTMUSP00000006064 VEGA | MGI Sequence Detail 252 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(213 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase
InterPro IPR024078 Putative deacetylase LmbE-like domain
Protein Ontology PR:000012699 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
References
(Earliest) J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)
Other
accession IDs
MGI:2685583

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory