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Grip2 Gene Detail
Summary
  • Symbol
    Grip2
  • Name
    glutamate receptor interacting protein 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681173
    NCBI Gene: 243547
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:91738490-91804231 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 40.80 cM, cytoband D2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1677 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681173
 protein coding gene Chr6:91738433-91820884 (-)
129S1/SvImJ ENSMUSG00200042598
 protein coding gene Chr6:88690301-88756098 (-)
A/J ENSMUSG00195039089
 protein coding gene Chr6:88409706-88475525 (-)
AKR/J ENSMUSG00220029744
 protein coding gene Chr6:87323053-87388794 (-)
BALB/cJ ENSMUSG00180016292
 protein coding gene Chr6:88774897-88840705 (-)
C3H/HeJ ENSMUSG00175024494
 protein coding gene Chr6:88592449-88658187 (+)
C57BL/6NJ ENSMUSG00215026725
 protein coding gene Chr6:88781068-88846814 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028657
 protein coding gene Chr6:87799534-87869364 (-)
CAST/EiJ ENSTCUG00005016756
 protein coding gene Chr6:88885834-88951647 (-)
CBA/J ENSMUSG00210041263
 protein coding gene Chr6:88564087-88629818 (-)
DBA/2J ENSMUSG00185041384
 protein coding gene Chr6:89108241-89174041 (-)
FVB/NJ ENSMUSG00205028387
 protein coding gene Chr6:87766024-87831793 (-)
JF1/MsJ ENSUMUG00000032539
 protein coding gene Chr6:88045041-88111110 (-)
LP/J ENSMUSG00230050015
 protein coding gene Chr6:90248095-90313884 (-)
NOD/ShiLtJ ENSMUSG00190033887
 protein coding gene Chr6:88178764-88244527 (-)
NZO/HlLtJ ENSMUSG00225039432
 protein coding gene Chr6:92250914-92316718 (-)
PWK/PhJ ENSLUMG00010032452
 protein coding gene Chr6:87463713-87530417 (-)
SPRET/EiJ ENSMSPG00010041043
 protein coding gene Chr6:89741234-89806121 (-)
WSB/EiJ ENSIUOG00005030466
 protein coding gene Chr6:89170263-89235946 (-)



Homology
more
  • Human Ortholog
    GRIP2, glutamate receptor interacting protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GRIP2, glutamate receptor interacting protein 2
  • Synonyms
    ABP
  • Links
    NCBI Gene ID: 80852
    UniProt: Q9C0E4

  • Chr Location
    3p25.1; chr3:14489107-14603017 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotypes from multigenic genotypes
    15 phenotype references
Homozygous null mice are born in numbers expected by the Mendelian ratio and show no overt phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    609
  • Tissues
    3
  • cDNA Data
    22
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030098 Ensembl Gene Model | MGI Sequence Detail 65742 C57BL/6J ±  kb
transcript ENSMUST00000162300 Ensembl | MGI Sequence Detail 5206 Not Applicable  
polypeptide ENSMUSP00000124709 Ensembl | MGI Sequence Detail 1042 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 2
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 15
  • Earliest
    J:54097 Bruckner K, et al., EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron. 1999 Mar;22(3):511-24
  • Latest
    J:386463 Rias E, et al., Protocol for isolation of total RNA from mouse whole cochlea using organic solvents. STAR Protoc. 2026 Mar 20;7(1):104376
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory