About   Help   FAQ
Ttc37 Gene Detail
Summary
  • Symbol
    Ttc37
  • Name
    tetratricopeptide repeat domain 37
  • Synonyms
    mKIAA0372
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679923
    NCBI Gene: 218343
Location & Maps
more
  • Sequence Map
    Chr13:76098734-76187983 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      89250 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    TTC37, tetratricopeptide repeat domain 37
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TTC37, tetratricopeptide repeat domain 37
    Orthology source: HGNC, HomoloGene
  • Synonyms
    KIAA0372, Ski3, THES
  • Links
    NCBI Gene ID: 9652
    neXtProt AC: NX_Q6PGP7

  • Chr Location
    5q15; chr5:95463895-95555005 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 40966
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: TTC37
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human TTC37 associations

Human Disease Mouse Models
       Trichohepatoenteric Syndrome 1; THES1   OMIM: 222470
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Gene trapped
    13
  • Genomic Mutations
    1 involving Ttc37
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033991 Ensembl Gene Model | MGI Sequence Detail 89250 C57BL/6J ±  kb
transcript ENSMUST00000091466 Ensembl | MGI Sequence Detail 5381 Not Applicable  
polypeptide ENSMUSP00000089045 Ensembl | MGI Sequence Detail 1563 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    991 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR006597 Sel1-like repeat
    IPR011990 Tetratricopeptide-like helical domain
    IPR019734 Tetratricopeptide repeat
    IPR001440 Tetratricopeptide repeat 1
    IPR013105 Tetratricopeptide repeat 2
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
less
  • All nucleic 70
    cDNA 70

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory