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Ttc37 Gene Detail
Summary
  • Symbol
    Ttc37
  • Name
    tetratricopeptide repeat domain 37
  • Synonyms
    mKIAA0372
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679923
    NCBI Gene: 218343
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:76098734-76190316 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 40.95 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    993 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679923
protein coding gene Chr13:76098730-76190318 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020778
protein coding gene Chr13:76642327-76736114 (+)
A/J MGP_AJ_G0020734
protein coding gene Chr13:74033756-74125743 (+)
AKR/J MGP_AKRJ_G0020707
protein coding gene Chr13:76277421-76366274 (+)
BALB/cJ MGP_BALBcJ_G0020730
protein coding gene Chr13:74518441-74606624 (+)
C3H/HeJ MGP_C3HHeJ_G0020524
protein coding gene Chr13:75985393-76080604 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021167
protein coding gene Chr13:79217727-79312042 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018735
protein coding gene Chr13:70840967-70930822 (+)
CAST/EiJ MGP_CASTEiJ_G0020042
protein coding gene Chr13:75063561-75155724 (+)
CBA/J MGP_CBAJ_G0020483
protein coding gene Chr13:82225148-82324480 (+)
DBA/2J MGP_DBA2J_G0020608
protein coding gene Chr13:73739538-73830623 (+)
FVB/NJ MGP_FVBNJ_G0020588
protein coding gene Chr13:72799532-72885539 (+)
LP/J MGP_LPJ_G0020681
protein coding gene Chr13:76918443-77002094 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020617
protein coding gene Chr13:80622148-80724262 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021207
protein coding gene Chr13:75603600-75697116 (+)
PWK/PhJ MGP_PWKPhJ_G0019795
protein coding gene Chr13:72653048-72743062 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019618
protein coding gene Chr13:71969757-72063334 (+)
WSB/EiJ MGP_WSBEiJ_G0020099
protein coding gene Chr13:76099941-76206322 (+)



Homology
more
  • Human Ortholog
    TTC37, tetratricopeptide repeat domain 37
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TTC37, tetratricopeptide repeat domain 37
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KIAA0372, Ski3, THES
  • Links
    NCBI Gene ID: 9652
    neXtProt AC: NX_Q6PGP7
    UniProt: Q6PGP7

  • Chr Location
    5q15; chr5:95463895-95555005 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 40966
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TTC37
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033991 Ensembl Gene Model | MGI Sequence Detail 91583 C57BL/6J ±  kb
transcript ENSMUST00000224386 Ensembl | MGI Sequence Detail 6976 Not Applicable  
polypeptide ENSMUSP00000153521 Ensembl | MGI Sequence Detail 1563 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR039226 Ski3/TTC37
    IPR011990 Tetratricopeptide-like helical domain superfamily
    IPR019734 Tetratricopeptide repeat
    IPR013026 Tetratricopeptide repeat-containing domain
Molecular
Reagents
less
  • All nucleic 71
    cDNA 71

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory