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Cpsf1 Gene Detail
Summary
  • Symbol
    Cpsf1
  • Name
    cleavage and polyadenylation specific factor 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679722
    NCBI Gene: 94230
  • Gene Overview
    MyGene.info: CPSF1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76595808-76607591 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 36.13 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679722
protein coding gene Chr15:76595803-76607591 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022000
protein coding gene Chr15:76679425-76693287 (-)
A/J MGP_AJ_G0021958
protein coding gene Chr15:73878544-73892706 (-)
AKR/J MGP_AKRJ_G0021941
protein coding gene Chr15:75887511-75899315 (-)
BALB/cJ MGP_BALBcJ_G0021967
protein coding gene Chr15:73907417-73919793 (-)
C3H/HeJ MGP_C3HHeJ_G0021739
protein coding gene Chr15:75931416-75945282 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022407
protein coding gene Chr15:79547495-79559294 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019936
protein coding gene Chr15:70537345-70549315 (-)
CAST/EiJ MGP_CASTEiJ_G0021258
protein coding gene Chr15:76736756-76749068 (-)
CBA/J MGP_CBAJ_G0021706
protein coding gene Chr15:82060593-82076246 (-)
DBA/2J MGP_DBA2J_G0021831
protein coding gene Chr15:73419996-73431772 (-)
FVB/NJ MGP_FVBNJ_G0021811
protein coding gene Chr15:72474544-72486796 (-)
LP/J MGP_LPJ_G0021902
protein coding gene Chr15:76772242-76786591 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021836
protein coding gene Chr15:87400724-87413748 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022427
protein coding gene Chr15:76161961-76173799 (-)
PWK/PhJ MGP_PWKPhJ_G0020999
protein coding gene Chr15:73583044-73594887 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020839
protein coding gene Chr15:75855518-75867377 (-)
WSB/EiJ MGP_WSBEiJ_G0021310
protein coding gene Chr15:76246791-76261069 (-)



Homology
more
  • Human Ortholog
    CPSF1, cleavage and polyadenylation specific factor 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CPSF1, cleavage and polyadenylation specific factor 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CPSF160, HSU37012, P/cl.18
  • Links
    NCBI Gene ID: 29894
    neXtProt AC: NX_Q10570
    UniProt: Q10570

  • Chr Location
    8q24.3; chr8:144393231-144409400 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 94230 NCBI Gene Model | MGI Sequence Detail 11784 C57BL/6J ±  kb
transcript NM_053193 RefSeq | MGI Sequence Detail 4538 C57BL/6  
polypeptide Q9EPU4 UniProt | EBI | MGI Sequence Detail 1441 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000005828 cleavage and polyadenylation specificity factor subunit 1
  • InterPro Domains
    IPR004871 Cleavage/polyadenylation specificity factor, A subunit, C-terminal
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
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  • All nucleic 182
    cDNA 181
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 52
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 5
    Phenotypes 26
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory