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Mblac1 Gene Detail
Summary
  • Symbol
    Mblac1
  • Name
    metallo-beta-lactamase domain containing 1
  • Synonyms
    MGC:49416
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679717
    NCBI Gene: 330216
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:138194314-138195621 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 76.98 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    30 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679717
protein coding gene Chr5:138194314-138195621 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030261
protein coding gene Chr5:142990433-142991740 (+)
A/J MGP_AJ_G0030229
protein coding gene Chr5:136808867-136810174 (+)
AKR/J MGP_AKRJ_G0030161
protein coding gene Chr5:141261328-141262635 (+)
BALB/cJ MGP_BALBcJ_G0030243
protein coding gene Chr5:138168469-138169776 (+)
C3H/HeJ MGP_C3HHeJ_G0029956
protein coding gene Chr5:141890347-141891654 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030690
protein coding gene Chr5:148343671-148344978 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027908
protein coding gene Chr5:130942836-130944142 (+)
CAST/EiJ MGP_CASTEiJ_G0029362
protein coding gene Chr5:141270988-141272297 (+)
CBA/J MGP_CBAJ_G0029927
protein coding gene Chr5:154220827-154222134 (+)
DBA/2J MGP_DBA2J_G0030075
protein coding gene Chr5:136708293-136709600 (+)
FVB/NJ MGP_FVBNJ_G0030033
protein coding gene Chr5:135872970-135874277 (+)
LP/J MGP_LPJ_G0030164
protein coding gene Chr5:143530420-143531727 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030064
protein coding gene Chr5:157046134-157047441 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030731
protein coding gene Chr5:141096870-141098177 (+)
PWK/PhJ MGP_PWKPhJ_G0029076
protein coding gene Chr5:135767161-135768468 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028912
protein coding gene Chr5:138657699-138659006 (+)
WSB/EiJ MGP_WSBEiJ_G0029437
protein coding gene Chr5:141786312-141787620 (+)



Homology
more
  • Human Ortholog
    MBLAC1, metallo-beta-lactamase domain containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MBLAC1, metallo-beta-lactamase domain containing 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 255374
    neXtProt AC: NX_A4D2B0
    UniProt: A4D2B0

  • Chr Location
    7q22.1; chr7:100126694-100128498 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 45596
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MBLAC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 330216 NCBI Gene Model | MGI Sequence Detail 1308 C57BL/6J ±  kb
transcript NM_177878 RefSeq | MGI Sequence Detail 1308 C57BL/6  
polypeptide Q8BWY4 UniProt | EBI | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory