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Cyp26c1 Gene Detail
Summary
  • Symbol
    Cyp26c1
  • Name
    cytochrome P450, family 26, subfamily c, polypeptide 1
  • Synonyms
    EG546726
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679699
    NCBI Gene: 546726
  • Gene Overview
    MyGene.info: CYP26C1
Location & Maps
more
  • Sequence Map
    Chr19:37685581-37693398 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7818 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 32.36 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    CYP26C1, cytochrome P450 family 26 subfamily C member 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CYP26C1, cytochrome P450 family 26 subfamily C member 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FFDD4
  • Links
    NCBI Gene ID: 340665
    neXtProt AC: NX_Q6V0L0
    UniProt: Q6V0L0

  • Chr Location
    10q23.33; chr10:93061264-93068697 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    21 phenotypes from multigenic genotypes
    3 phenotype references
Mice homozygous for a knock-out allele are viable and exhibit normal CNS development with no apparent anatomical defects.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062432 Ensembl Gene Model | MGI Sequence Detail 7818 C57BL/6J ±  kb
transcript ENSMUST00000073391 Ensembl | MGI Sequence Detail 1747 Not Applicable  
polypeptide ENSMUSP00000073105 Ensembl | MGI Sequence Detail 518 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    135 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
Molecular
Reagents
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  • All nucleic 5
    cDNA 4
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:3643384
References
more
  • Summaries
    All 31
    Developmental Gene Expression 17
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:85714 Tahayato A, et al., Cyp26C1 encodes a novel retinoic acid-metabolizing enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine development. Gene Expr Patterns. 2003 Aug;3(4):449-54
  • Latest
    J:222442 Li BI, et al., The orphan GPCR, Gpr161, regulates the retinoic acid and canonical Wnt pathways during neurulation. Dev Biol. 2015 Jun 1;402(1):17-31

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory