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Cyp26c1 Gene Detail
Summary
  • Symbol
    Cyp26c1
  • Name
    cytochrome P450, family 26, subfamily c, polypeptide 1
  • Synonyms
    EG546726
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679699
    NCBI Gene: 546726
  • Gene Overview
    MyGene.info: CYP26C1
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr19:37685581-37693398 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 32.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679699
protein coding gene Chr19:37685195-37693398 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025083
protein coding gene Chr19:36680447-36688254 (+)
A/J MGP_AJ_G0025059
protein coding gene Chr19:34903952-34912030 (+)
AKR/J MGP_AKRJ_G0025027
protein coding gene Chr19:36097746-36106196 (+)
BALB/cJ MGP_BALBcJ_G0025057
protein coding gene Chr19:34991723-34999531 (+)
C3H/HeJ MGP_C3HHeJ_G0024816
protein coding gene Chr19:36160783-36168578 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025498
protein coding gene Chr19:37748417-37756229 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022917
protein coding gene Chr19:34265456-34273225 (+)
CAST/EiJ MGP_CASTEiJ_G0024283
protein coding gene Chr19:36013991-36025225 (+)
CBA/J MGP_CBAJ_G0024793
protein coding gene Chr19:39493662-39501453 (+)
DBA/2J MGP_DBA2J_G0024925
protein coding gene Chr19:34757812-34765638 (+)
FVB/NJ MGP_FVBNJ_G0024886
protein coding gene Chr19:34565781-34573575 (+)
LP/J MGP_LPJ_G0025011
protein coding gene Chr19:36781802-36789608 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024917
protein coding gene Chr19:39302296-39310109 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025556
protein coding gene Chr19:36179546-36187356 (+)
PWK/PhJ MGP_PWKPhJ_G0024035
protein coding gene Chr19:34610629-34618538 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023835
protein coding gene Chr19:35027427-35035301 (+)
WSB/EiJ MGP_WSBEiJ_G0024350
protein coding gene Chr19:36267474-36275285 (+)



Homology
more
  • Human Ortholog
    CYP26C1, cytochrome P450 family 26 subfamily C member 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    CYP26C1, cytochrome P450 family 26 subfamily C member 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FFDD4
  • Links
    NCBI Gene ID: 340665
    neXtProt AC: NX_Q6V0L0
    UniProt: Q6V0L0

  • Chr Location
    10q23.33; chr10:93061264-93068697 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    22 phenotypes from multigenic genotypes
    3 phenotype references
Mice homozygous for a knock-out allele are viable and exhibit normal CNS development with no apparent anatomical defects.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062432 Ensembl Gene Model | MGI Sequence Detail 7818 C57BL/6J ±  kb
transcript ENSMUST00000073391 Ensembl | MGI Sequence Detail 1747 Not Applicable  
polypeptide ENSMUSP00000073105 Ensembl | MGI Sequence Detail 518 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR036396 Cytochrome P450 superfamily
Molecular
Reagents
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  • All nucleic 5
    cDNA 4
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:3643384
References
more
  • Summaries
    All 38
    Developmental Gene Expression 23
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:85714 Tahayato A, et al., Cyp26C1 encodes a novel retinoic acid-metabolizing enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine development. Gene Expr Patterns. 2003 Aug;3(4):449-54
  • Latest
    J:266575 Metzler MA, et al., RDH10-mediated retinol metabolism and RARalpha-mediated retinoic acid signaling are required for submandibular salivary gland initiation (doi: 10.1242/dev.164822). Development. 2018 Aug 30;145(17)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory