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Cyp26c1
Gene Detail
Symbol

Name
ID
Cyp26c1
cytochrome P450, family 26, subfamily c, polypeptide 1
MGI:2679699
Synonyms
EG546726
Feature Type
protein coding gene
Genetic Map
Chromosome 19
32.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:37685680-37693307 bp, + strand
From NCBI annotation of GRCm38

  7628 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:28089  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CYP26C1
Gene Tree: Cyp26c1

Human
homologs
CYP26C1, cytochrome P450, family 26, subfamily C, polypeptide 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 340665
neXtProt AC: NX_Q6V0L0

Human Synonyms: FFDD4

Human Chr (Location): 10q23.33; chr10:93061264-93068697 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human CYP26C1

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele are viable and exhibit normal CNS development with no apparent anatomical defects.
 
Interactions
Cyp26c1 interacts with 10 markers (Mir127, Mir214, Mir335, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (16 records)
Data Summary: Results (81)    Tissues (46)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 77
RT-PCR 4
cDNA source data(4)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: GEISHA CYP26C1 ; Xenbase LOC100489980 ; ZFIN cyp26c1    NEW 
Molecular
reagents
All nucleic(5) cDNA(4) Primer pair(1)
Microarray probesets(1)
Other database
links
Ensembl Gene Model ENSMUSG00000062432 (Evidence)
Entrez Gene 546726 (Evidence)
UniGene 457750
NIA Mouse Gene Index U186739
Consensus CDS Project CCDS50428.1
International Mouse Phenotyping Consortium Status Cyp26c1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 546726 NCBI Gene Model | MGI Sequence Detail 7628 C57BL/6J ±  kb
transcript NM_001105201 RefSeq | MGI Sequence Detail 1557 C57BL/6 
polypeptide NP_001098671 RefSeq | MGI Sequence Detail 518 C57BL/6 

For the selected sequences
All sequences(11) RefSeq(3) UniProt(1)
Polymorphisms
SNPs within 2kb(133 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
Protein Ontology PR:000006109 cytochrome P450 26C1
References
(Earliest) J:85714 Tahayato A, et al., Cyp26C1 encodes a novel retinoic acid-metabolizing enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine development. Gene Expr Patterns. 2003 Aug;3(4):449-54
(Latest) J:213451 Karpinski BA, et al., Dysphagia and disrupted cranial nerve development in a mouse model of DiGeorge (22q11) deletion syndrome. Dis Model Mech. 2014 Feb;7(2):245-57
All references(31)
Other
accession IDs
MGI:3643384

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory