Paqr3
Gene Detail

Symbol Name ID

Paqr3 progestin and adipoQ receptor family member III MGI:2679683

Synonyms

6330415A20Rik, RKTG

Feature Type

protein coding gene

Genetic Map

Chromosome 5

47.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr5:97082329-97111596 bp, - strand From VEGA annotation of GRCm38   29268 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:71077  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: membrane receptor, ADIPOR type
Gene Tree: Paqr3

Human homologs

Human Homolog		PAQR3, progestin and adipoQ receptor family member III
NCBI Gene ID		152559
neXtProt AC		NX_Q6TCH7
Human Synonyms		RKTG
Human Chr (Location)		4q21.21; chr4:79839094-79860582 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(5)
 

Targeted deletion of this gene causes faster chemical carcinogen-induced skin cell proliferation, higher epidermal thickness, increased number and size of skin papillomas, shorter tumor latency and delayed tumor regression. Heterozygotes develop tumors earlier and more frequently than control mice.

 

Gene Ontology (GO) classifications

All GO classifications: (4 annotations)

Component

Golgi apparatus, integral to membrane, ...

External Resources: FuncBase

Expression

cDNA source data(29)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(29) cDNA(29)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000023913 (Evidence)
Ensembl Gene Model	ENSMUSG00000055725 (Evidence)
Entrez Gene	231474 (Evidence)
UniGene	332505
Consensus CDS Project	CCDS19451.1
International Mouse Knockout Project Status	Paqr3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000023913	VEGA Gene Model | MGI Sequence Detail	29268	C57BL/6J
transcript	OTTMUST00000058414	VEGA | MGI Sequence Detail	1375	Not Applicable
polypeptide	OTTMUSP00000028298	VEGA | MGI Sequence Detail	311	Not Applicable

All sequences(38) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(177 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004254	Hly-III-related
Protein Ontology	PR:000012275	progestin and adipoQ receptor family member 3

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193153 Wang X, et al., PAQR3 plays a suppressive role in the tumorigenesis of colorectal cancers. Carcinogenesis. 2012 Nov;33(11):2228-35
All references(29)

Other accession IDs

MGI:1917996