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Paqr3
Gene Detail
 Symbol
Name
ID
Paqr3
progestin and adipoQ receptor family member III
MGI:2679683
Synonyms 6330415A20Rik, RKTG
Feature Type protein coding gene
Genetic Map
Chromosome 5
47.29 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:97082329-97111596 bp, - strand
From VEGA annotation of GRCm38

  29268 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:71077  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: membrane receptor, ADIPOR type
Gene Tree: Paqr3

Human
homologs
Human Homolog PAQR3, progestin and adipoQ receptor family member III
NCBI Gene ID 152559
neXtProt AC  NX_Q6TCH7
Human Synonyms  RKTG
Human Chr (Location)  4q21.21; chr4:78887278-78939428 (-)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
 
Targeted deletion of this gene causes faster chemical carcinogen-induced skin cell proliferation, higher epidermal thickness, increased number and size of skin papillomas, shorter tumor latency and delayed tumor regression. Heterozygotes develop tumors earlier and more frequently than control mice.
 
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process negative regulation of MAP kinase activity, negative regulation of neuron projection development, ...
Component Golgi apparatus, integral component of membrane, ...
Function receptor activity
External Resources: FuncBase
Expression
cDNA source data(26)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(26) cDNA(26)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000023913 (Evidence)
Ensembl Gene ModelENSMUSG00000055725 (Evidence)
Entrez Gene231474 (Evidence)
UniGene332505
Consensus CDS ProjectCCDS19451.1
International Mouse Knockout Project StatusPaqr3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023913 VEGA Gene Model | MGI Sequence Detail 29268 C57BL/6J ±  kb
transcript OTTMUST00000058417 VEGA | MGI Sequence Detail 2257 Not Applicable 
polypeptide OTTMUSP00000028300 VEGA | MGI Sequence Detail 311 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(8) UniProt(4)
Polymorphisms SNPs within 2kb(189 from dbSNP Build 137)    SNPs within 2kb including multiple locations(193)
Protein-related
information
ResourceIDDescription
InterPro IPR004254 Hly-III-related
Protein Ontology PR:000012275 progestin and adipoQ receptor family member 3
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:204073 Wang L, et al., PAQR3 has modulatory roles in obesity, energy metabolism, and leptin signaling. Endocrinology. 2013 Dec;154(12):4525-35
All references(31)
Other
accession IDs
MGI:1917996

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory