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Slitrk5
Gene Detail
Symbol

Name
ID
Slitrk5
SLIT and NTRK-like family, member 5
MGI:2679448
Synonyms
2610019D03Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 14
57.86 cM, cytoband E3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:111675115-111683134 bp, + strand
From Ensembl annotation of GRCm38

  8020 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9193  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slitrk5

Human
homologs
Human Homolog SLITRK5, SLIT and NTRK-like family, member 5
NCBI Gene ID 26050
neXtProt AC  NX_O94991
Human Synonyms  bA364G4.2, LRRC11
Human Chr (Location)  13q31.2; chr13:87671034-87679616 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele have abnormal medium spiny neuron morphology and exhibit behavioral abnormalities.
 
Human Diseases Modeled Using Mouse Slitrk5 (1)    Alleles Annotated to Human Diseases(1)   
Interactions
Slitrk5 interacts with 278 markers (Mir1b, Mir7-1, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process adult behavior, axonogenesis, ...
Component integral component of membrane, membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (73)    Tissues (73)    Images (12)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 44
Northern blot 29
cDNA source data(7)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(8) Other(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000033214 (Evidence)
Entrez Gene75409 (Evidence)
DFCITC1582134, TC1597661, TC1650578
DoTSDT.101270283, DT.55108081
NIA Mouse Gene IndexU015948
Consensus CDS ProjectCCDS27328.1
International Mouse Knockout Project StatusSlitrk5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033214 Ensembl Gene Model | MGI Sequence Detail 8020 C57BL/6J ±  kb
transcript ENSMUST00000042767 Ensembl | MGI Sequence Detail 4806 Not Applicable 
polypeptide ENSMUSP00000041499 Ensembl | MGI Sequence Detail 957 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(9) UniProt(3)
Polymorphisms
SNPs within 2kb(92 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
InterPro IPR001611 Leucine-rich repeat
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
InterPro IPR003591 Leucine-rich repeat, typical subtype
Protein Ontology PR:000015241 SLIT and NTRK-like protein 5
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:194542 Ghai R, et al., Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E643-52
All references(29)
Disease annotation references (1)
Other
accession IDs
MGI:1922659

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory