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Klhl17
Gene Detail
 Symbol
Name
ID
Klhl17
kelch-like 17
MGI:2678948
Synonyms actinfilin
Feature Type protein coding gene
Genetic Map
Chromosome 4
88.63 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr4:156229044-156234857 bp, - strand
From NCBI annotation of GRCm38

  5814 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:27075  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: kelch-like protein, gigaxonin type
Gene Tree: Klhl17

Human
homologs
Human Homolog KLHL17, kelch-like family member 17
NCBI Gene ID 339451
neXtProt AC  NX_Q6TDP4
Human Chr (Location)  1p36.33; chr1:960587-965719 (+)  GRCh38
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Klhl17 interacts with 180 markers (Mir18, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process actin cytoskeleton organization
Component actin cytoskeleton, cell junction, ...
Function actin binding, actin filament binding, ...
External Resources: FuncBase
Expression
cDNA source data(35)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(35) cDNA(35)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000078484 (Evidence)
Entrez Gene231003 (Evidence)
UniGene423038
Consensus CDS ProjectCCDS38999.1
International Mouse Knockout Project StatusKlhl17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 231003 NCBI Gene Model | MGI Sequence Detail 5814 C57BL/6J ±  kb
transcript NM_198305 RefSeq | MGI Sequence Detail 3014 C57BL/6 
polypeptide Q6TDP3 UniProt | EBI | MGI Sequence Detail 640 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(4)
Polymorphisms SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011705 BTB/Kelch-associated
InterPro IPR013069 BTB/POZ
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR015916 Galactose oxidase, beta-propeller
InterPro IPR011043 Galactose oxidase/kelch, beta-propeller
InterPro IPR017096 Kelch-like protein, gigaxonin
InterPro IPR006652 Kelch repeat type 1
InterPro IPR015915 Kelch-type beta propeller
Protein Ontology PR:000009379 kelch-like protein 17
Graphical View of Protein Domain Structure
References (Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(21)
Other
accession IDs
MGI:2140408

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory