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Dolk
Gene Detail
 Symbol
Name
ID
Dolk
dolichol kinase
MGI:2677836
Synonyms MGC:36683, mKIAA1094, Tmem15
Feature Type protein coding gene
Genetic Map
Chromosome 2
21.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:30284231-30286334 bp, - strand
From VEGA annotation of GRCm38

  2104 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8940  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Dolk

Human
homologs
Human Homolog DOLK, dolichol kinase
NCBI Gene ID 22845
neXtProt AC  NX_Q9UPQ8
Human Synonyms  CDG1M, DK, DK1, SEC59, TMEM15
Human Chr (Location)  9q34.11; chr9:128945530-128947733 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human DOLK
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dolk interacts with 47 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process dolichyl monophosphate biosynthetic process, phosphorylation
Component endoplasmic reticulum, integral component of endoplasmic reticulum membrane, ...
Function dolichol kinase activity, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(47)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(47) cDNA(47)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000016769 (Evidence)
Ensembl Gene ModelENSMUSG00000075419 (Evidence)
Entrez Gene227697 (Evidence)
UniGene26690
DFCITC1579465
NIA Mouse Gene IndexU022473
EC2.7.1.108
Consensus CDS ProjectCCDS15877.1
International Mouse Knockout Project StatusDolk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016769 VEGA Gene Model | MGI Sequence Detail 2104 C57BL/6J ±  kb
transcript OTTMUST00000040713 VEGA | MGI Sequence Detail 2104 Not Applicable 
polypeptide OTTMUSP00000018203 VEGA | MGI Sequence Detail 534 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Protein-related
information
ResourceIDDescription
InterPro IPR026566 Dolichol kinase
Protein Ontology PR:000006635 dolichol kinase
References (Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory