About   Help   FAQ
Dolk
Gene Detail
Symbol

Name
ID
Dolk
dolichol kinase
MGI:2677836
Synonyms
MGC:36683, mKIAA1094, Tmem15
Feature Type
protein coding gene
Genetic Map
Chromosome 2
21.49 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:30284231-30286334 bp, - strand
From VEGA annotation of GRCm38

  2104 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8940  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DOLK
Gene Tree: Dolk

Human
homologs
DOLK, dolichol kinase
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 22845
neXtProt AC: NX_Q9UPQ8

Human Synonyms: CDG1M, DK, DK1, SEC59, TMEM15

Human Chr (Location): 9q34.11; chr9:128945530-128947733 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DOLK

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Endonuclease-mediated(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Dolk interacts with 47 markers (Mir19a, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(47)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dolk    NEW 
Molecular
reagents
All nucleic(47) cDNA(47)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000016769 (Evidence)
Ensembl Gene Model ENSMUSG00000075419 (Evidence)
Entrez Gene 227697 (Evidence)
UniGene 26690
DFCI TC1579465
NIA Mouse Gene Index U022473
EC 2.7.1.108
Consensus CDS Project CCDS15877.1
International Mouse Phenotyping Consortium Status Dolk
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016769 VEGA Gene Model | MGI Sequence Detail 2104 C57BL/6J ±  kb
transcript OTTMUST00000040713 VEGA | MGI Sequence Detail 2104 Not Applicable 
polypeptide OTTMUSP00000018203 VEGA | MGI Sequence Detail 534 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Protein-related
information
ResourceIDDescription
InterPro IPR026566 Dolichol kinase
Protein Ontology PR:000006635 dolichol kinase
References
(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory