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Qrfpr Gene Detail
Summary
  • Symbol
    Qrfpr
  • Name
    pyroglutamylated RFamide peptide receptor
  • Synonyms
    AQ27, Gpr103
  • Feature Type
    protein coding gene
  • IDs
    MGI:2677633
    NCBI Gene: 229214
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:36179426-36222275 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 17.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    313 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2677633
protein coding gene Chr3:36179424-36222313 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027157
protein coding gene Chr3:33949329-33999711 (-)
A/J MGP_AJ_G0027117
protein coding gene Chr3:33323552-33366087 (-)
AKR/J MGP_AKRJ_G0027086
protein coding gene Chr3:33924315-33968026 (-)
BALB/cJ MGP_BALBcJ_G0027129
protein coding gene Chr3:33080624-33135016 (-)
C3H/HeJ MGP_C3HHeJ_G0026872
protein coding gene Chr3:33993502-34037065 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027575
protein coding gene Chr3:35598714-35651329 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024936
protein coding gene Chr3:31032683-31074255 (-)
CAST/EiJ MGP_CASTEiJ_G0026325
protein coding gene Chr3:33836312-33892487 (-)
CBA/J MGP_CBAJ_G0026849
protein coding gene Chr3:36553419-36604399 (-)
DBA/2J MGP_DBA2J_G0026983
protein coding gene Chr3:32784381-32827492 (-)
FVB/NJ MGP_FVBNJ_G0026951
protein coding gene Chr3:32237975-32287618 (-)
LP/J MGP_LPJ_G0027095
protein coding gene Chr3:34729397-34779460 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026971
protein coding gene Chr3:38985516-39033316 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027634
protein coding gene Chr3:33780412-33823443 (-)
PWK/PhJ MGP_PWKPhJ_G0026058
protein coding gene Chr3:32432378-32476054 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025870
protein coding gene Chr3:33155673-33202503 (-)
WSB/EiJ MGP_WSBEiJ_G0026399
protein coding gene Chr3:33796026-33849537 (-)



Homology
more
  • Human Ortholog
    QRFPR, pyroglutamylated RFamide peptide receptor
  • Vertebrate Orthologs
    9
  • Human Ortholog
    QRFPR, pyroglutamylated RFamide peptide receptor
    Orthology source: HGNC, HomoloGene
  • Synonyms
    AQ27, GPR103, SP9155
  • Links
    NCBI Gene ID: 84109
    neXtProt AC: NX_Q96P65
    UniProt: Q96P65

  • Chr Location
    4q27; chr4:121328642-121381029 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Qrfpr mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a mutation diisplay kyphosis with abnormal vertebrae morphology and development including osteopenia of the vertebrae.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 229214 NCBI Gene Model | MGI Sequence Detail 42850 C57BL/6J ±  kb
transcript NM_198192 RefSeq | MGI Sequence Detail 1816 Not Specified  
polypeptide P83861 UniProt | EBI | MGI Sequence Detail 433 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 32
    Diseases 2
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:204140 Loktev AV, et al., Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia. Cell Rep. 2013 Dec 12;5(5):1316-29

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory