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Sipa1l2 Gene Detail
Summary
  • Symbol
    Sipa1l2
  • Name
    signal-induced proliferation-associated 1 like 2
  • Synonyms
    mKIAA1389
  • Feature Type
    protein coding gene
  • IDs
    MGI:2676970
    NCBI Gene: 244668
  • Gene Overview
    MyGene.info: SIPA1L2
Location & Maps
more
  • Sequence Map
    Chr8:125418063-125492710 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      74648 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 73.63 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    SIPA1L2, signal induced proliferation associated 1 like 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SIPA1L2, signal induced proliferation associated 1 like 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SPAL2
  • Links
    NCBI Gene ID: 57568
    neXtProt AC: NX_Q9P2F8

  • Chr Location
    1q42.2; chr1:232397965-232630696 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001995 Ensembl Gene Model | MGI Sequence Detail 74648 C57BL/6J ±  kb
transcript ENSMUST00000108775 Ensembl | MGI Sequence Detail 6365 Not Applicable  
polypeptide ENSMUSP00000104405 Ensembl | MGI Sequence Detail 1722 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1974 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000014882 signal-induced proliferation-associated 1-like protein 2
  • InterPro Domains
    IPR001478 PDZ domain
    IPR000331 Rap GTPase activating protein domain
    IPR031203 Signal-induced proliferation-associated 1-like protein 2
    IPR021818 Signal-induced proliferation-associated 1-like protein, C-terminal
Molecular
Reagents
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  • All nucleic 78
    cDNA 78

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:202816 Wajapeyee N, et al., Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. Genes Dev. 2013 Oct 15;27(20):2221-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory