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Mir26a-1 Gene Detail
Summary
  • Symbol
    Mir26a-1
  • Name
    microRNA 26a-1
  • Synonyms
    Mirn26a, Mirn26a-1, mmu-mir-26a-1
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676900
    NCBI Gene: 387218
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr9:118860864-118860953 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 71.32 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    6 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676900
miRNA gene Chr9:118860864-118860953 (+)
129S1/SvImJ MGP_129S1SvImJ_G0009248
miRNA gene Chr9:121745760-121745849 (+)
A/J MGP_AJ_G0009228
miRNA gene Chr9:117248840-117248929 (+)
AKR/J MGP_AKRJ_G0009218
miRNA gene Chr9:120283206-120283295 (+)
BALB/cJ MGP_BALBcJ_G0009212
miRNA gene Chr9:117113573-117113662 (+)
C3H/HeJ MGP_C3HHeJ_G0009152
miRNA gene Chr9:120752450-120752539 (+)
C57BL/6NJ MGP_C57BL6NJ_G0009455
miRNA gene Chr9:125087233-125087322 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0008304
miRNA gene Chr9:114440951-114441040 (+)
CAST/EiJ MGP_CASTEiJ_G0008983
miRNA gene Chr9:120707103-120707192 (+)
CBA/J MGP_CBAJ_G0009119
miRNA gene Chr9:129789256-129789345 (+)
DBA/2J MGP_DBA2J_G0009149
miRNA gene Chr9:116684245-116684334 (+)
FVB/NJ MGP_FVBNJ_G0009166
miRNA gene Chr9:115524792-115524881 (+)
LP/J MGP_LPJ_G0009246
miRNA gene Chr9:122090454-122090543 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0009133
miRNA gene Chr9:130780417-130780506 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0009425
miRNA gene Chr9:120669986-120670075 (+)
PWK/PhJ MGP_PWKPhJ_G0008908
miRNA gene Chr9:117094816-117094905 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008745
miRNA gene Chr9:120762979-120763068 (+)
WSB/EiJ MGP_WSBEiJ_G0009077
miRNA gene Chr9:120555957-120556046 (+)



Homology
more
  • Human Ortholog
    MIR26A1, microRNA 26a-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR26A1, microRNA 26a-1
  • Synonyms
    MIR26A, mir-26a-1, MIRN26A1
  • Links
    NCBI Gene ID: 407015

  • Chr Location
    chr3:37969404-37969480 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    20 phenotypes from multigenic genotypes
    2 images
    17 phenotype references
Mice double homozygous for Mir26a-1 and Mir26a-2 fed a high-fat diet exhibit beta cell hyperproliferation and hyperplasia with increased obesity, and insulin resistance.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 387218 NCBI Gene Model | MGI Sequence Detail 90 C57BL/6J ±  kb
transcript NR_029742 RefSeq | MGI Sequence Detail 90 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 5
    Primer pair 2
    Other 3
Other Database
Links
less
miRBase MI0000573
References
more
  • Summaries
    All 65
    Developmental Gene Expression 9
    Gene Ontology 6
    Phenotypes 17
  • Earliest
    J:12215 Chubb C, Oligotriche and quaking gene mutations. Phenotypic effects on mouse spermatogenesis and testicular steroidogenesis. J Androl. 1992 Jul-Aug;13(4):312-7
  • Latest
    J:343881 Zeng H, et al., AP2-microRNA-26a overexpression reduces visceral fat mass and blood lipids. Mol Cell Endocrinol. 2021 May 15;528:111217

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/05/2024
MGI 6.23
The Jackson Laboratory