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Mir22
Gene Detail
Symbol

Name
ID
Mir22
microRNA 22
MGI:2676896
Synonyms
Mirn22, mmu-mir-22
Feature Type
miRNA gene
Genetic Map
Chromosome 11
45.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:75463716-75463810 bp, + strand
From miRBase annotation of GRCm38

  95 bp   ±  kb flank

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Mouse Genome Browser
Vertebrate
homology
Gene Tree: Mir22
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Genomic Mutations involving Mir22 (1)
 
Mice homozygous for a knock-out allele exhibit impaired cardiac function following treatment with dobutamine or transverse aortic constriction. Another homozygous knock-out allele shows altered cardiac responses to isoproterenol-induced stress.
 
Interactions
Mir22 interacts with 7485 markers (0610030E20Rik, 0610037L13Rik, 1110002E22Rik, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (1 annotations)
Process cellular response to amino acid stimulus
Expression
Literature Summary: (3 records)
Data Summary: Results (14)    Tissues (6)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 14
Other mouse links: GEO   Expression Atlas
Molecular
reagents
All nucleic(2) Primer pair(1) Other(1)
Other database
links
Ensembl Gene Model ENSMUSG00000065529 (Evidence)
Entrez Gene 387141 (Evidence)
miRBase MI0000570
International Mouse Phenotyping Consortium Status Mir22
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 387141 NCBI Gene Model | MGI Sequence Detail 95 C57BL/6J ±  kb
transcript NR_029739 RefSeq | MGI Sequence Detail 95 C57BL/6 

For the selected sequences
All sequences(5) RefSeq(1)
Polymorphisms
SNPs within 2kb(8 from dbSNP Build 137)
References
(Earliest) J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
(Latest) J:212491 Nam JW, et al., Global analyses of the effect of different cellular contexts on microRNA targeting. Mol Cell. 2014 Mar 20;53(6):1031-43
All references(20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory