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Mir217 Gene Detail
Summary
  • Symbol
    Mir217
  • Name
    microRNA 217
  • Synonyms
    Mirn217, mmu-mir-217
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676893
    NCBI Gene: 387213
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:28713728-28713835 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 16.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676893
miRNA gene Chr11:28713728-28713835 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007791
miRNA gene Chr11:26749207-26749314 (+)
A/J MGP_AJ_G0007787
miRNA gene Chr11:25781906-25782013 (+)
AKR/J MGP_AKRJ_G0007761
miRNA gene Chr11:26601534-26601641 (+)
BALB/cJ MGP_BALBcJ_G0007764
miRNA gene Chr11:25938797-25938904 (+)
C3H/HeJ MGP_C3HHeJ_G0007711
miRNA gene Chr11:26542101-26542208 (+)
C57BL/6NJ MGP_C57BL6NJ_G0007942
miRNA gene Chr11:27732260-27732367 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007090
miRNA gene Chr11:24453141-24453248 (+)
CAST/EiJ MGP_CASTEiJ_G0007606
miRNA gene Chr11:26585063-26585170 (+)
CBA/J MGP_CBAJ_G0007683
miRNA gene Chr11:28998574-28998681 (+)
DBA/2J MGP_DBA2J_G0007718
miRNA gene Chr11:25630058-25630165 (+)
FVB/NJ MGP_FVBNJ_G0007735
miRNA gene Chr11:25435557-25435664 (+)
LP/J MGP_LPJ_G0007795
miRNA gene Chr11:27010485-27010592 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007706
miRNA gene Chr11:30015339-30015446 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0007940
miRNA gene Chr11:26741164-26741271 (+)
PWK/PhJ MGP_PWKPhJ_G0007535
miRNA gene Chr11:25735468-25735575 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007432
miRNA gene Chr11:26424284-26424391 (+)
WSB/EiJ MGP_WSBEiJ_G0007672
miRNA gene Chr11:26416205-26416312 (+)



Homology
more
  • Human Ortholog
    MIR217, microRNA 217
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR217, microRNA 217
  • Synonyms
    mir-217, MIRN217
  • Links
    NCBI Gene ID: 406999

  • Chr Location
    chr2:55982967-55983076 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from multigenic genotypes
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Genomic Mutations
    1 involving Mir217
  • Find Mice (IMSR)
Mice homozygous for a null allele exhibit pancreatic acinar-to-ductal metaplasia in vitro and increased susceptibility to induced pancreatitis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 387213 NCBI Gene Model | MGI Sequence Detail 108 C57BL/6J ±  kb
transcript NR_029828 RefSeq | MGI Sequence Detail 108 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 2
    Other 2
Other Database
Links
less
miRBase MI0000731
References
more
  • Summaries
    All 22
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:297754 de Yebenes VG, et al., Aging-Associated miR-217 Aggravates Atherosclerosis and Promotes Cardiovascular Dysfunction. Arterioscler Thromb Vasc Biol. 2020 Oct;40(10):2408-2424

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory