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Mir205 Gene Detail
Summary
  • Symbol
    Mir205
  • Name
    microRNA 205
  • Synonyms
    Mirn205, mmu-mir-205
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676880
    NCBI Gene: 387201
Location & Maps
more
  • Sequence Map
    Chr1:193507463-193507530 bp, - strand
  • From miRBase annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      68 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 97.82 cM
  • Mapping Data
    1 experiment
Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    16 phenotypes from 3 alleles in 3 genetic backgrounds
    1 images
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Targeted
    5
Mice homozygous for a targeted deletion exhibit embryonic lethality. Mice homozygous for a different knock-out allele exhibit postnatal lethality with abnormal hair follicle development.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
  • Other Mouse Links
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 387201 NCBI Gene Model | MGI Sequence Detail 68 C57BL/6J ±  kb
transcript NR_029592 RefSeq | MGI Sequence Detail 68 C57BL/6  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    55 from dbSNP Build 142
Molecular
Reagents
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  • All nucleic 1
    Primer pair 1
Other Database
Links
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References
more
  • Summaries
    All 25
    Developmental Gene Expression 10
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:84908 Lagos-Quintana M, et al., New microRNAs from mouse and human. RNA. 2003 Feb;9(2):175-9
  • Latest
    J:213793 Chao CH, et al., MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis. J Clin Invest. 2014 Jul 1;124(7):3093-106

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory