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Mir1a-1 Gene Detail
Summary
  • Symbol
    Mir1a-1
  • Name
    microRNA 1a-1
  • Synonyms
    Mirn1-1, Mirn1b, Mirn1c, Mirn1d, mmu-mir-1-1, mmu-mir-1a-1
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676869
    NCBI Gene: 387136
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr2:180389048-180389124 bp, + strand
  • From miRBase annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 102.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676869
miRNA gene Chr2:180389048-180389124 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008622
miRNA gene Chr2:186904778-186904854 (+)
A/J MGP_AJ_G0008612
miRNA gene Chr2:179229668-179229744 (+)
AKR/J MGP_AKRJ_G0008601
miRNA gene Chr2:184604087-184604163 (+)
BALB/cJ MGP_BALBcJ_G0008599
miRNA gene Chr2:179693626-179693702 (+)
C3H/HeJ MGP_C3HHeJ_G0008541
miRNA gene Chr2:184941806-184941882 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008811
miRNA gene Chr2:192297576-192297652 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007786
miRNA gene Chr2:169921520-169921596 (+)
CAST/EiJ MGP_CASTEiJ_G0008396
miRNA gene Chr2:183192367-183192443 (+)
CBA/J MGP_CBAJ_G0008505
miRNA gene Chr2:199300877-199300953 (+)
DBA/2J MGP_DBA2J_G0008539
miRNA gene Chr2:178328212-178328288 (+)
FVB/NJ MGP_FVBNJ_G0008560
miRNA gene Chr2:176936153-176936229 (+)
LP/J MGP_LPJ_G0008629
miRNA gene Chr2:186911073-186911149 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008523
miRNA gene Chr2:201907002-201907078 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008794
miRNA gene Chr2:184557540-184557616 (+)
PWK/PhJ MGP_PWKPhJ_G0008321
miRNA gene Chr2:175837966-175838042 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008177
miRNA gene Chr2:181053582-181053658 (+)
WSB/EiJ MGP_WSBEiJ_G0008480
miRNA gene Chr2:185538923-185538999 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotypes from 1 allele in 2 genetic backgrounds
    18 phenotypes from multigenic genotypes
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit partial lethality before weaning and subtle cardiac defects, including intermittent atrial arrhythmias, mild ventricular dilation, and conduction abnormalities. Lethality is strain-dependent.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 387136 NCBI Gene Model | MGI Sequence Detail 77 C57BL/6J ±  kb
    transcript NR_029528 RefSeq | MGI Sequence Detail 77 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 5
      Primer pair 2
      Other 3
    Other Database
    Links
    less
    Other
    Accession IDs
    less
    MGI:2676870, MGI:2676871
    References
    more
    • Summaries
      All 55
      Developmental Gene Expression 28
      Gene Ontology 7
      Phenotypes 5
    • Earliest
      J:14774 Jakoby WB, et al., Glutathione transferases: nomenclature. Biochem Pharmacol. 1984 Aug 15;33(16):2539-40
    • Latest
      J:262205 Wust S, et al., Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster. Cell Metab. 2018 May 1;27(5):1026-1039.e6

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    01/15/2019
    MGI 6.13
    The Jackson Laboratory