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Mir125a Gene Detail
Summary
  • Symbol
    Mir125a
  • Name
    microRNA 125a
  • Synonyms
    Mirn125a, mmu-mir-125a
  • Feature Type
    miRNA gene
  • IDs
    MGI:2676809
    NCBI Gene: 387235
  • Member of
    Mirc9 cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr17:17830812-17830879 bp, + strand
  • From miRBase annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 10.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    13 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676809
miRNA gene Chr17:17830812-17830879 (.)
129S1/SvImJ MGP_129S1SvImJ_G0008307
miRNA gene Chr17:15836901-15836968 (+)
A/J MGP_AJ_G0008294
miRNA gene Chr17:15482405-15482472 (+)
AKR/J MGP_AKRJ_G0008277
miRNA gene Chr17:15558037-15558104 (+)
BALB/cJ MGP_BALBcJ_G0008279
miRNA gene Chr17:15427857-15427924 (+)
C3H/HeJ MGP_C3HHeJ_G0008221
miRNA gene Chr17:15774511-15774578 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008476
miRNA gene Chr17:16624384-16624451 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007532
miRNA gene Chr17:13331257-13331324 (+)
CAST/EiJ MGP_CASTEiJ_G0008089
miRNA gene Chr17:15585624-15585691 (+)
CBA/J MGP_CBAJ_G0008190
miRNA gene Chr17:17193265-17193332 (+)
DBA/2J MGP_DBA2J_G0008223
miRNA gene Chr17:15196748-15196815 (+)
FVB/NJ MGP_FVBNJ_G0008247
miRNA gene Chr17:15007352-15007419 (+)
LP/J MGP_LPJ_G0008306
miRNA gene Chr17:15831092-15831159 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008211
miRNA gene Chr17:16776823-16776890 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008466
miRNA gene Chr17:15744688-15744755 (+)
PWK/PhJ MGP_PWKPhJ_G0008010
miRNA gene Chr17:14828428-14828495 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007899
miRNA gene Chr17:14831272-14831339 (+)
WSB/EiJ MGP_WSBEiJ_G0008169
miRNA gene Chr17:16033668-16033735 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decreased regulatory T cell numbers and increased susceptibility to experimental autoimmune encephalomyelitis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 387235 NCBI Gene Model | MGI Sequence Detail 68 C57BL/6J ±  kb
transcript NR_029539 RefSeq | MGI Sequence Detail 68 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 7
    Primer pair 3
    Other 4
Other Database
Links
less
References
more
  • Summaries
    All 41
    Developmental Gene Expression 11
    Gene Ontology 9
    Phenotypes 3
  • Earliest
    J:84907 Lagos-Quintana M, et al., Identification of tissue-specific microRNAs from mouse. Curr Biol. 2002 Apr 30;12(9):735-9
  • Latest
    J:251488 Li H, et al., RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions. Cell Stem Cell. 2017 Apr 6;20(4):462-477.e6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory