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Birc7 Gene Detail
Summary
  • Symbol
    Birc7
  • Name
    baculoviral IAP repeat-containing 7 (livin)
  • Synonyms
    KIAP, Livin, ML-IAP
  • Feature Type
    protein coding gene
  • IDs
    MGI:2676458
    NCBI Gene: 329581
  • Gene Overview
    MyGene.info: BIRC7
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:180929023-180934010 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 103.53 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    60 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676458
protein coding gene Chr2:180928152-180934010 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027005
protein coding gene Chr2:187496117-187501111 (+)
A/J MGP_AJ_G0026971
protein coding gene Chr2:179781931-179786918 (+)
AKR/J MGP_AKRJ_G0026941
protein coding gene Chr2:185172270-185177257 (+)
BALB/cJ MGP_BALBcJ_G0026980
protein coding gene Chr2:180242846-180247840 (+)
C3H/HeJ MGP_C3HHeJ_G0026721
protein coding gene Chr2:185530612-185535599 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027426
protein coding gene Chr2:192920285-192925272 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024791
protein coding gene Chr2:170468811-170473857 (+)
CAST/EiJ MGP_CASTEiJ_G0026180
protein coding gene Chr2:183777117-183782078 (+)
CBA/J MGP_CBAJ_G0026698
protein coding gene Chr2:199906028-199911022 (+)
DBA/2J MGP_DBA2J_G0026836
protein coding gene Chr2:178874884-178879871 (+)
FVB/NJ MGP_FVBNJ_G0026802
protein coding gene Chr2:177488046-177493033 (+)
LP/J MGP_LPJ_G0026937
protein coding gene Chr2:187503998-187508992 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026821
protein coding gene Chr2:202488880-202493874 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027485
protein coding gene Chr2:185140486-185145473 (+)
PWK/PhJ MGP_PWKPhJ_G0025916
protein coding gene Chr2:176400444-176405423 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025716
protein coding gene Chr2:181630168-181635149 (+)
WSB/EiJ MGP_WSBEiJ_G0026252
protein coding gene Chr2:186126628-186131615 (+)



Homology
more
  • Human Ortholog
    BIRC7, baculoviral IAP repeat containing 7
  • Vertebrate Orthologs
    6
  • Human Ortholog
    BIRC7, baculoviral IAP repeat containing 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KIAP, LIVIN, MLIAP, ML-IAP, RNF50
  • Links
    NCBI Gene ID: 79444
    neXtProt AC: NX_Q96CA5
    UniProt: Q96CA5

  • Chr Location
    20q13.33; chr20:63235883-63240507 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Mice homozygous for a knock-out allele exhibit normal retinal morphology and function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038840 Ensembl Gene Model | MGI Sequence Detail 4988 C57BL/6J ±  kb
transcript ENSMUST00000108875 Ensembl | MGI Sequence Detail 1178 Not Applicable  
polypeptide ENSMUSP00000104503 Ensembl | MGI Sequence Detail 285 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:84168 Reed JC, et al., Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res. 2003 Jun;13(6B):1376-88
  • Latest
    J:230953 De Maria A, et al., Birc7: A Late Fiber Gene of the Crystalline Lens. Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4823-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory