About   Help   FAQ
Adam6a Gene Detail
Summary
  • Symbol
    Adam6a
  • Name
    a disintegrin and metallopeptidase domain 6A
  • Synonyms
    Adam6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2676316
    NCBI Gene: 238406
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr12:113543908-113546414 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 62.12 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2676316
protein coding gene Chr12:113543908-113546465 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020177
protein coding gene Chr12:116099710-116102410 (+)
A/J MGP_AJ_G0020132
protein coding gene Chr12:111549085-111551784 (+)
AKR/J MGP_AKRJ_G0020107
protein coding gene Chr12:114840892-114843485 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0019919
protein coding gene Chr12:115307253-115377670 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020562
protein coding gene Chr12:119645300-119647893 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0019459
protein coding gene Chr12:110256293-110259775 (+)
CBA/J MGP_CBAJ_G0019886
protein coding gene Chr12:124230697-124233705 (+)
DBA/2J MGP_DBA2J_G0020004
protein coding gene Chr12:111113843-111116540 (+)
FVB/NJ MGP_FVBNJ_G0019989
protein coding gene Chr12:109920336-109923034 (+)
LP/J MGP_LPJ_G0020077
protein coding gene Chr12:115895458-115898051 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020591
protein coding gene Chr12:114291681-114294383 (+)
PWK/PhJ MGP_PWKPhJ_G0019222
protein coding gene Chr12:105769702-105776443 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019025
protein coding gene Chr12:108476750-108479001 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ADAM6, ADAM metallopeptidase domain 6 (pseudogene)
  • Vertebrate Orthologs
    2
  • Human Ortholog
    ADAM6, ADAM metallopeptidase domain 6 (pseudogene)
    Orthology source: HGNC
  • Synonyms
    C14orf96, tMDCIV
  • Links
    NCBI Gene ID: 8755

  • Chr Location
    14q32.33; chr14:105969731-105972269 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 238406 NCBI Gene Model | MGI Sequence Detail 2507 C57BL/6J ±  kb
transcript NM_174885 RefSeq | MGI Sequence Detail 2507 C57BL/6  
polypeptide NP_777479 RefSeq | MGI Sequence Detail 754 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    Genomic 2
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:89726 Choi I, et al., Characterization and comparative genomic analysis of intronless Adams with testicular gene expression. Genomics. 2004 Apr;83(4):636-46
  • Latest
    J:208620 Murphy AJ, et al., Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5153-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/04/2018
MGI 6.13
The Jackson Laboratory