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Gramd4 Gene Detail
Summary
  • Symbol
    Gramd4
  • Name
    GRAM domain containing 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2676308
    NCBI Gene: 223752
Location & Maps
more
  • Sequence Map
    Chr15:86057695-86137634 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      79940 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 40.48 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    GRAMD4, GRAM domain containing 4
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GRAMD4, GRAM domain containing 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    dA59H18.1, DIP, dJ439F8.1
  • Links
    NCBI Gene ID: 23151
    neXtProt AC: NX_Q6IC98

  • Chr Location
    22q13.31; chr22:46576017-46682758 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    3 involving Gramd4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025710 VEGA Gene Model | MGI Sequence Detail 79940 C57BL/6J ±  kb
transcript OTTMUST00000063318 VEGA | MGI Sequence Detail 4115 Not Applicable  
polypeptide OTTMUSP00000031292 VEGA | MGI Sequence Detail 633 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    859 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000008218 GRAM domain-containing protein 4
  • InterPro Domains
    IPR004182 GRAM domain
Molecular
Reagents
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  • All nucleic 86
    cDNA 86

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 1
    Phenotypes 24
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory