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Gzmn
Gene Detail
 Symbol
Name
ID
Gzmn
granzyme N
MGI:2675494
Synonyms GrN
Feature Type protein coding gene
Genetic Map
Chromosome 14
28.19 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:56165797-56174596 bp, - strand
From Ensembl annotation of GRCm38

  8800 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:87221  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: trypsin
Gene Tree: Gzmn

Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (129)    Tissues (14)    Images (23)
Theiler Stages: 23
Assay TypeResults
RNA in situ 129
cDNA source data(2)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(2) cDNA(2)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000015443 (Evidence)
Entrez Gene245839 (Evidence)
UniGene207063
DFCITC1595649
DoTSDT.102553529, DT.94130940
NIA Mouse Gene IndexU035604
Consensus CDS ProjectCCDS27145.1
International Mouse Knockout Project StatusGzmn
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015443 Ensembl Gene Model | MGI Sequence Detail 8800 C57BL/6J ±  kb
transcript ENSMUST00000015587 Ensembl | MGI Sequence Detail 953 Not Applicable 
polypeptide ENSMUSP00000015587 Ensembl | MGI Sequence Detail 248 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(6) UniProt(2)
Polymorphisms SNPs within 2kb(182 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
References (Earliest) J:85357 Sattar R, et al., Bioinformatics of granzymes: sequence comparison and structural studies on granzyme family by homology modeling. Biochem Biophys Res Commun. 2003 Sep 5;308(4):726-35
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(21)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory