Gzmn
Gene Detail

Symbol Name ID

Gzmn granzyme N MGI:2675494

Synonyms

GrN

Feature Type

protein coding gene

Genetic Map

Chromosome 14

28.19 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr14:56165797-56174596 bp, - strand From Ensembl annotation of GRCm38   8800 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:87221  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: trypsin
Gene Tree: Gzmn

Alleles and phenotypes

All alleles(1) : Targeted(1)

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	proteolysis
Component	cellular_component
Function	hydrolase activity, peptidase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (129)    Tissues (14)    Images (23)
Theiler Stages: 23

Assay Type	Results
RNA in situ	129

cDNA source data(2)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(2) cDNA(2)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000015443 (Evidence)
Entrez Gene	245839 (Evidence)
UniGene	207063
DFCI	TC1595649
DoTS	DT.102553529, DT.94130940
NIA Mouse Gene Index	U035604
Consensus CDS Project	CCDS27145.1
International Mouse Knockout Project Status	Gzmn

Sequences

Length	Strain/Species
genomic	ENSMUSG00000015443	Ensembl Gene Model | MGI Sequence Detail	8800	C57BL/6J
transcript	ENSMUST00000015587	Ensembl | MGI Sequence Detail	953	Not Applicable
polypeptide	ENSMUSP00000015587	Ensembl | MGI Sequence Detail	248	Not Applicable

All sequences(15) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(65 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site

References

(Earliest) J:85357 Sattar R, et al., Bioinformatics of granzymes: sequence comparison and structural studies on granzyme family by homology modeling. Biochem Biophys Res Commun. 2003 Sep 5;308(4):726-35
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(22)