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Gzmn
Gene Detail
Symbol

Name
ID
Gzmn
granzyme N
MGI:2675494
Synonyms
GrN
Feature Type
protein coding gene
Genetic Map
Chromosome 14
28.19 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:56165797-56174596 bp, - strand
From Ensembl annotation of GRCm38

  8800 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:87221  Vertebrate Homology Class
1 mouse; 1 rat

Protein SuperFamily: trypsin
Gene Tree: Gzmn

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Gzmn interacts with 28 markers (Mir18, Mir22, Mir27a, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (129)    Tissues (14)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 129
cDNA source data(2)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(2) cDNA(2)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000015443 (Evidence)
Entrez Gene 245839 (Evidence)
UniGene 207063
DFCI TC1595649
DoTS DT.102553529, DT.94130940
NIA Mouse Gene Index U035604
Consensus CDS Project CCDS27145.1
International Mouse Phenotyping Consortium Status Gzmn
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015443 Ensembl Gene Model | MGI Sequence Detail 8800 C57BL/6J ±  kb
transcript ENSMUST00000015587 Ensembl | MGI Sequence Detail 953 Not Applicable 
polypeptide ENSMUSP00000015587 Ensembl | MGI Sequence Detail 248 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(6) UniProt(2)
Polymorphisms
SNPs within 2kb(182 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR009003 Peptidase S1, PA clan
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR001254 Serine proteases, trypsin domain
References
(Earliest) J:85357 Sattar R, et al., Bioinformatics of granzymes: sequence comparison and structural studies on granzyme family by homology modeling. Biochem Biophys Res Commun. 2003 Sep 5;308(4):726-35
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(20)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory