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Adm2 Gene Detail
Summary
  • Symbol
    Adm2
  • Name
    adrenomedullin 2
  • Synonyms
    IMD, intermedin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2675256
    NCBI Gene: 223780
  • Gene Overview
    MyGene.info: ADM2
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr15:89322972-89324728 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1757 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 44.81 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ADM2, adrenomedullin 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ADM2, adrenomedullin 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AM2, dJ579N16.4
  • Links
    NCBI Gene ID: 79924
    neXtProt AC: NX_Q7Z4H4
    UniProt: Q7Z4H4

  • Chr Location
    22q13.33; chr22:50481724-50486440 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054136 Ensembl Gene Model | MGI Sequence Detail 1757 C57BL/6J ±  kb
transcript ENSMUST00000066991 Ensembl | MGI Sequence Detail 1043 Not Applicable  
polypeptide ENSMUSP00000064761 Ensembl | MGI Sequence Detail 150 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    19 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    Genomic 1
    cDNA 4

    Microarray probesets 2
References
more
  • Summaries
    All 50
    Diseases 1
    Gene Ontology 5
    Phenotypes 24
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:237374 Lv Y, et al., Adrenomedullin 2 Enhances Beiging in White Adipose Tissue Directly in an Adipocyte-autonomous Manner and Indirectly through Activation of M2 Macrophages. J Biol Chem. 2016 Nov 04;291(45):23390-23402

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory