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Bpifb3 Gene Detail
Summary
  • Symbol
    Bpifb3
  • Name
    BPI fold containing family B, member 3
  • Synonyms
    Rya3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2675077
    NCBI Gene: 378700
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:153918230-153932996 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 75.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    378 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2675077
protein coding gene Chr2:153918230-153932996 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026702
protein coding gene Chr2:158627421-158642166 (+)
A/J MGP_AJ_G0026668
protein coding gene Chr2:152239144-152254028 (+)
AKR/J MGP_AKRJ_G0026639
protein coding gene Chr2:156717814-156732580 (+)
BALB/cJ MGP_BALBcJ_G0026678
protein coding gene Chr2:152576649-152591385 (+)
C3H/HeJ MGP_C3HHeJ_G0026420
protein coding gene Chr2:157094469-157109205 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027127
protein coding gene Chr2:163252778-163267544 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024497
protein coding gene Chr2:145812715-145827452 (+)
CAST/EiJ MGP_CASTEiJ_G0025881
protein coding gene Chr2:157362816-157377746 (+)
CBA/J MGP_CBAJ_G0026399
protein coding gene Chr2:169250915-169265651 (+)
DBA/2J MGP_DBA2J_G0026534
protein coding gene Chr2:151465301-151480190 (+)
FVB/NJ MGP_FVBNJ_G0026500
protein coding gene Chr2:149913778-149928527 (+)
LP/J MGP_LPJ_G0026639
protein coding gene Chr2:158746138-158760883 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026522
protein coding gene Chr2:173232257-173247152 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027182
protein coding gene Chr2:156609209-156623975 (+)
PWK/PhJ MGP_PWKPhJ_G0025615
protein coding gene Chr2:150995406-151010329 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025418
protein coding gene Chr2:155466114-155480896 (+)
WSB/EiJ MGP_WSBEiJ_G0025951
protein coding gene Chr2:157517683-157532653 (+)



Homology
more
  • Human Ortholog
    BPIFB3, BPI fold containing family B member 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    BPIFB3, BPI fold containing family B member 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C20orf185, LPLUNC3, RYA3
  • Links
    NCBI Gene ID: 359710
    neXtProt AC: NX_P59826
    UniProt: P59826

  • Chr Location
    20q11.21; chr20:33055331-33073637 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 378700 NCBI Gene Model | MGI Sequence Detail 14767 C57BL/6J ±  kb
transcript NM_194357 RefSeq | MGI Sequence Detail 1842 Not Specified  
polypeptide Q80ZU7 UniProt | EBI | MGI Sequence Detail 473 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000009899 BPI fold-containing family B member 3
  • InterPro Domains
    IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain superfamily
    IPR032951 BPI fold-containing family B member 3
    IPR032942 BPI/LBP/Plunc family
    IPR001124 Lipid-binding serum glycoprotein, C-terminal
    IPR017942 Lipid-binding serum glycoprotein, N-terminal
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:89705 Bingle CD, et al., Phylogenetic and evolutionary analysis of the PLUNC gene family. Protein Sci. 2004 Feb;13(2):422-30
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory