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Bicral Gene Detail
Summary
  • Symbol
    Bicral
  • Name
    BRD4 interacting chromatin remodeling complex associated protein like
  • Synonyms
    BC032203, Gltscr1l, mKIAA0240
  • Feature Type
    protein coding gene
  • IDs
    MGI:2673855
    NCBI Gene: 210982
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr17:46798116-46831413 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      33298 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 22.90 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    BICRAL, BRD4 interacting chromatin remodeling complex associated protein like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BICRAL, BRD4 interacting chromatin remodeling complex associated protein like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    GLTSCR1L, KIAA0240
  • Links
    NCBI Gene ID: 23506
    neXtProt AC: NX_Q6AI39
    UniProt: Q6AI39

  • Chr Location
    6p21.1; chr6:42746958-42868560 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 19366
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BICRAL
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele display abnormal embryo turning, embryonic growth retardation, cardiac hypertrophy, and complete embryonic lethality during organogenesis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036568 Ensembl Gene Model | MGI Sequence Detail 33298 C57BL/6J ±  kb
    transcript ENSMUST00000040624 Ensembl | MGI Sequence Detail 6579 Not Applicable  
    polypeptide ENSMUSP00000044833 Ensembl | MGI Sequence Detail 1074 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      378 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR038842 BRD4-interacting chromatin-remodeling complex-associated protein
      IPR015671 GLTSCR protein, conserved region
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 10
      Primer pair 1
      Other 1

      Microarray probesets 7
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 7
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    10/16/2018
    MGI 6.12
    The Jackson Laboratory