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Lncpint Gene Detail
Summary
  • Symbol
    Lncpint
  • Name
    long non-protein coding RNA, Trp53 induced transcript
  • Synonyms
    AB041803, Lincpint, Linc-Pint, MNCb-1768, Pint
  • Feature Type
    lincRNA gene
  • IDs
    MGI:2673128
    NCBI Gene: 232685
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:31093563-31218474 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 12.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    781 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2673128
lincRNA gene Chr6:31082565-31220488 (-)
129S1/SvImJ MGP_129S1SvImJ_G0006921
lincRNA gene Chr6:28999134-29124818 (-)
A/J MGP_AJ_G0006915
lincRNA gene Chr6:27774900-27899111 (-)
AKR/J MGP_AKRJ_G0006885
lincRNA gene Chr6:28704109-28828550 (-)
BALB/cJ MGP_BALBcJ_G0006891
lincRNA gene Chr6:27895941-28021851 (-)
C3H/HeJ MGP_C3HHeJ_G0006836
lincRNA gene Chr6:28714187-28841488 (-)
C57BL/6NJ MGP_C57BL6NJ_G0007056
lincRNA gene Chr6:29817144-29951226 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0006304
lincRNA gene Chr6:25937015-26060423 (-)
CAST/EiJ MGP_CASTEiJ_G0006753
lincRNA gene Chr6:28488635-28617057 (-)
CBA/J MGP_CBAJ_G0006818
lincRNA gene Chr6:30996657-31123806 (-)
DBA/2J MGP_DBA2J_G0006838
lincRNA gene Chr6:27671528-27797066 (-)
FVB/NJ MGP_FVBNJ_G0006861
lincRNA gene Chr6:27466450-27592224 (-)
LP/J MGP_LPJ_G0006921
lincRNA gene Chr6:29186933-29317439 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0006842
lincRNA gene Chr6:33385668-33515441 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0007058
lincRNA gene Chr6:28593882-28723936 (-)
PWK/PhJ MGP_PWKPhJ_G0006695
lincRNA gene Chr6:27247628-27374267 (-)
SPRET/EiJ MGP_SPRETEiJ_G0006604
lincRNA gene Chr6:28282627-28409084 (-)
WSB/EiJ MGP_WSBEiJ_G0006808
lincRNA gene Chr6:28517596-28646652 (-)



Homology
more
  • Human Ortholog
    LINC-PINT, long intergenic non-protein coding RNA, p53 induced transcript
  • Human Ortholog
    LINC-PINT, long intergenic non-protein coding RNA, p53 induced transcript
    Orthology source: HGNC
  • Synonyms
    LincRNA-Pint, MKLN1-AS1, PINT
  • Links
    NCBI Gene ID: 378805

  • Chr Location
    7q32.3; chr7:130877562-131109916 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 1 allele in 2 genetic backgrounds
    1 images
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display decreased body weight. Mice homozygous for a different null allele show premature aging phenotypes including progressive fur loss and muscle weakness, lordokyphosis, reduced body fat and bone mineral density, a slower growth rate, and reduced survival.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic 232685 NCBI Gene Model | MGI Sequence Detail 124912 C57BL/6J ±  kb
transcript NR_110469 RefSeq | MGI Sequence Detail 1714 C57BL/6  
polypeptide Q8K5E3 UniProt | EBI | MGI Sequence Detail 96 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 2
    Genomic 1
    cDNA 1

    Microarray probesets 2
References
more
  • Summaries
    All 19
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:233815 Lai KM, et al., Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs. PLoS One. 2015;10(4):e0125522

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory