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Arhgef17 Gene Detail
Summary
  • Symbol
    Arhgef17
  • Name
    Rho guanine nucleotide exchange factor (GEF) 17
  • Synonyms
    mKIAA0337
  • Feature Type
    protein coding gene
  • IDs
    MGI:2673002
    NCBI Gene: 207212
Location & Maps
more
  • Sequence Map
    Chr7:100869752-100932107 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      62356 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 54.45 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ARHGEF17, Rho guanine nucleotide exchange factor 17
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARHGEF17, Rho guanine nucleotide exchange factor 17
    Orthology source: HomoloGene, HGNC
  • Synonyms
    p164-RhoGEF, P164RHOGEF, RHOGEF17, TEM4
  • Links
    NCBI Gene ID: 9828
    neXtProt AC: NX_Q96PE2

  • Chr Location
    11q13.4; chr11:73305939-73369380 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Arhgef17
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000059372 VEGA Gene Model | MGI Sequence Detail 62356 C57BL/6J ±  kb
transcript OTTMUST00000145749 VEGA | MGI Sequence Detail 10190 Not Applicable  
polypeptide OTTMUSP00000075940 VEGA | MGI Sequence Detail 2057 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    486 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000004252 rho guanine nucleotide exchange factor 17
  • InterPro Domains
    IPR000219 Dbl homology (DH) domain
    IPR011993 PH domain-like
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
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  • All nucleic 99
    cDNA 99

    Microarray probesets 7
Other
Accession IDs
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MGI:2141948, MGI:2142267
References
more
  • Summaries
    All 31
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory