About   Help   FAQ
Clec18a Gene Detail
Summary
  • Symbol
    Clec18a
  • Name
    C-type lectin domain family 18, member A
  • Synonyms
    Mrcl
  • Feature Type
    protein coding gene
  • IDs
    MGI:2672935
    NCBI Gene: 353287
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:111069496-111092424 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 57.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    69 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2672935
protein coding gene Chr8:111058920-111092426 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034135
protein coding gene Chr8:113778360-113824877 (-)
A/J MGP_AJ_G0034114
protein coding gene Chr8:109172595-109207577 (-)
AKR/J MGP_AKRJ_G0034041
protein coding gene Chr8:112363706-112404002 (-)
BALB/cJ MGP_BALBcJ_G0034108
protein coding gene Chr8:109351580-109384071 (-)
C3H/HeJ MGP_C3HHeJ_G0033819
protein coding gene Chr8:113087554-113125894 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034628
protein coding gene Chr8:117778941-117818652 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031570
protein coding gene Chr8:102152772-102185875 (-)
CAST/EiJ MGP_CASTEiJ_G0033146
protein coding gene Chr8:112702748-112741536 (-)
CBA/J MGP_CBAJ_G0033793
protein coding gene Chr8:121787028-121826728 (-)
DBA/2J MGP_DBA2J_G0033948
protein coding gene Chr8:108461238-108496981 (-)
FVB/NJ MGP_FVBNJ_G0033892
protein coding gene Chr8:107422800-107455090 (-)
LP/J MGP_LPJ_G0034038
protein coding gene Chr8:113964239-113998438 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033938
protein coding gene Chr8:124678684-124718491 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034647
protein coding gene Chr8:112337360-112377172 (-)
PWK/PhJ MGP_PWKPhJ_G0032849
protein coding gene Chr8:108043143-108075712 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032688
protein coding gene Chr8:111017209-111052619 (-)
WSB/EiJ MGP_WSBEiJ_G0033262
protein coding gene Chr8:113022108-113057038 (-)



Homology
more
  • Human Ortholog
    CLEC18A, C-type lectin domain family 18 member A
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CLEC18A, C-type lectin domain family 18 member A
    Orthology source: HGNC
  • Synonyms
    MRCL, MRCL1, MRLP2
  • Links
    NCBI Gene ID: 348174
    neXtProt AC: NX_A5D8T8
    UniProt: A5D8T8

  • Chr Location
    16q22.1; chr16:69950233-69968478 (+)  GRCh38.p7

  • Human Ortholog
    CLEC18B, C-type lectin domain family 18 member B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRCL2
  • Links
    NCBI Gene ID: 497190
    neXtProt AC: NX_Q6UXF7
    UniProt: Q6UXF7

  • Chr Location
    16q23.1; chr16:74408631-74422248 (-)  GRCh38.p7

  • Human Ortholog
    CLEC18C, C-type lectin domain family 18 member C
    Orthology source: HGNC
  • Synonyms
    MRCL, MRCL3
  • Links
    NCBI Gene ID: 283971
    neXtProt AC: NX_Q8NCF0
    UniProt: Q8NCF0

  • Chr Location
    16q22.1; chr16:70173322-70187147 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 353287 NCBI Gene Model | MGI Sequence Detail 22929 C57BL/6J ±  kb
transcript NM_181549 RefSeq | MGI Sequence Detail 1836 C57BL/6  
polypeptide Q7TSQ1 UniProt | EBI | MGI Sequence Detail 534 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:187047 Gerber SD, et al., Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory