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Col27a1
Gene Detail
Symbol

Name
ID
Col27a1
collagen, type XXVII, alpha 1
MGI:2672118
Synonyms
5730512J02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 4
33.96 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:63214004-63334991 bp, + strand
From VEGA annotation of GRCm38

  120988 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69400  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: COL27A1
Gene Tree: Col27a1

Human
homologs
COL27A1, collagen, type XXVII, alpha 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 85301
neXtProt AC: NX_Q8IZC6

Human Synonyms: STLS

Human Chr (Location): 9q32; chr9:114130331-114312516 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human COL27A1

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for an in frame deletion display neonatal lethality, respiratory failure, and severe chondrodysplasia.
 
Interactions
Col27a1 interacts with 248 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (245)    Tissues (54)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 212
RT-PCR 33
cDNA source data(29)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase col27a1 ; ZFIN col27a1a, col27a1b    NEW 
Molecular
reagents
All nucleic(33) Genomic(1) cDNA(29) Primer pair(3)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000000244 (Evidence)
Ensembl Gene Model ENSMUSG00000045672 (Evidence)
Entrez Gene 373864 (Evidence)
UniGene 194116
DFCI TC1590419, TC1586272, TC1593458, TC1630508, TC1621042, TC1610957, TC1597027, TC1651469
DoTS DT.87026828, DT.487483, DT.101266944, DT.101283556, DT.91372979, DT.94127230, DT.91596889
NIA Mouse Gene Index U004401
Consensus CDS Project CCDS18250.1
International Mouse Phenotyping Consortium Status Col27a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000244 VEGA Gene Model | MGI Sequence Detail 120988 C57BL/6J ±  kb
transcript OTTMUST00000000701 VEGA | MGI Sequence Detail 7612 Not Applicable 
polypeptide OTTMUSP00000000312 VEGA | MGI Sequence Detail 1845 Not Applicable 

For the selected sequences
All sequences(76) RefSeq(18) UniProt(3)
Polymorphisms
SNPs within 2kb(1099 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008160 Collagen triple helix repeat
InterPro IPR013320 Concanavalin A-like lectin/glucanase, subgroup
InterPro IPR000885 Fibrillar collagen, C-terminal
InterPro IPR001791 Laminin G domain
Protein Ontology PR:000005710 collagen alpha-1(XXVII) chain
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:182341 Plumb DA, et al., Collagen XXVII organises the pericellular matrix in the growth plate. PLoS One. 2011;6(12):e29422
All references(34)
Other
accession IDs
MGI:1913902, MGI:2140286

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory