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Thsd4 Gene Detail
Summary
  • Symbol
    Thsd4
  • Name
    thrombospondin, type I, domain containing 4
  • Synonyms
    ADAMTSL6, B230114P05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2672033
    NCBI Gene: 207596
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:59966931-60522046 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 32.38 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3898 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2672033
 protein coding gene Chr9:59966931-60522113 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034909
 protein coding gene Chr9:59357827-59939837 (-)
A/J MGP_AJ_G0034889
 protein coding gene Chr9:57450064-58008337 (-)
AKR/J MGP_AKRJ_G0034819
 protein coding gene Chr9:58786727-59351888 (-)
BALB/cJ MGP_BALBcJ_G0034882
 protein coding gene Chr9:57168388-57723516 (-)
C3H/HeJ MGP_C3HHeJ_G0034592
 protein coding gene Chr9:59258820-59828476 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035401
 protein coding gene Chr9:60982824-61579917 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032312
 protein coding gene Chr9:57163750-57715559 (-)
CAST/EiJ MGP_CASTEiJ_G0033913
 protein coding gene Chr9:59356711-59937013 (-)
CBA/J MGP_CBAJ_G0034563
 protein coding gene Chr9:63141991-63750195 (-)
DBA/2J MGP_DBA2J_G0034722
 protein coding gene Chr9:57255260-57809122 (-)
FVB/NJ MGP_FVBNJ_G0034664
 protein coding gene Chr9:56526261-57081877 (-)
LP/J MGP_LPJ_G0034805
 protein coding gene Chr9:59649904-60231538 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034707
 protein coding gene Chr9:64598194-65190943 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035423
 protein coding gene Chr9:58797512-59372414 (-)
PWK/PhJ MGP_PWKPhJ_G0033617
 protein coding gene Chr9:57326223-57895507 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033450
 protein coding gene Chr9:59059139-59647042 (-)
WSB/EiJ MGP_WSBEiJ_G0034026
 protein coding gene Chr9:58733542-59307405 (-)



Homology
more
  • Human Ortholog
    THSD4, thrombospondin type 1 domain containing 4
  • Vertebrate Orthologs
    7
  • Human Ortholog
    THSD4, thrombospondin type 1 domain containing 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ADAMTSL6, ADAMTSL-6, FVSY9334, PRO34005
  • Links
    NCBI Gene ID: 79875
    neXtProt AC: NX_Q6ZMP0
    UniProt: Q6ZMP0

  • Chr Location
    15q23; chr15:71115616-71783383 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    47
  • cDNA Data
    10
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032289 Ensembl Gene Model | MGI Sequence Detail 555116 C57BL/6J ±  kb
    transcript ENSMUST00000171654 Ensembl | MGI Sequence Detail 8522 Not Applicable  
    polypeptide ENSMUSP00000131418 Ensembl | MGI Sequence Detail 1018 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2143095
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 6
      Gene Ontology 4
      Phenotypes 4
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:196039 Howden R, et al., Cardiac physiologic and genetic predictors of hyperoxia-induced acute lung injury in mice. Am J Respir Cell Mol Biol. 2012 Apr;46(4):470-8
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    01/19/2021
    MGI 6.16     		The Jackson Laboratory